CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027142
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Adenylate cyclase 3, isoform CRA_b 
Protein Synonyms/Alias
 MKIAA0511 protein 
Gene Name
 Adcy3 
Gene Synonyms/Alias
 mKIAA0511; mCG_116984 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
299HVADEMLKDMKKDESubiquitination[1]
434LGGVLGQKRWQYDVWubiquitination[1]
1052MLRIGMNKGGVLAGVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Lyase; Nucleotide-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1150 AA 
Protein Sequence
KQPAANMPRN QGFSDPEYSA EYSAEYSVSL PSDPDRGVGR THEISVRNSG SCLCLPRFMR 60
LTFVPESLEN LYQTYFKRQR HETLLVLVVF AALFDCYVVV MCAVVFSSDK LAPLMVAGFG 120
LVLDIILFVL CKKGLLPDRV SRKVVPYLLW LLISAQIFSY LGLNFSRAHA ASDTVGWQAF 180
FVFSFFITLP LSLSPIVIIS VVSCVVHTLV LGVTVAQQQQ DELEGMQLLR EILANVFLYL 240
CAIIVGIMSY YMADRKHRKA FLEARQSLEV KMNLEEQSQQ QENLMLSILP KHVADEMLKD 300
MKKDESQKDQ QQFNTMYMYR HENVSILFAD IVGFTQLSSA CSAQELVKLL NELFARFDKL 360
AAKYHQLRIK ILGDCYYCIC GLPDYREDHA VCSILMGLAM VEAISYVREK TKTGVDMRVG 420
VHTGTVLGGV LGQKRWQYDV WSTDVTVANK MEAGGIPGRV HISQSTMDCL KGEFDVEPGD 480
GGSRCDYLDE KGIETYLIIA SKPEVKKTAQ NGLNGSAVPN GAPASSKPSS PALIETKEPN 540
GSAHASGSTS EEAEEQEAQA DNPSFPNPRR RLRLQDLADR VVDASEDEHE LNQLLNEALL 600
ERESAQVVKK RNTFLLTMRF MDPEMETRYS VEKEKQSGAA FSCSCVVLFC TAMVEILIDP 660
WLMTNYVTFV VGEVLLLILT ICSMAAIFPR SFPKKLVAFS SWIDRTRWAR NTWAMLAIFI 720
LVMANVVDML SCLQYYMGPY NMTAGMELDG GCMENPKYYN YVAVLSLIAT IMLVQVSHMV 780
KLTLMLLVTG AVTALNLYAW CPVFDEYDHK RFQEKDSPMV ALEKMQVLAT PGLNGTDRLP 840
LVPSKYSMTV MMFVMMLSFY YFSRHVEKLA RTLFLWKIEV HDQKERVYEM RRWNEALVTN 900
MLPEHVARHF LGSKKRDEEL YSQSYDEIGV MFASLPNFAD FYTEESINNG GIECLRFLNE 960
IISDFDSLLD NPKFRVITKI KTIGSTYMAA SGVTPDVNTN GFTSSSKEEK SDKERWQHLA 1020
DLADFALAMK DTLTNINNQS FNNFMLRIGM NKGGVLAGVI GARKPHYDIW GNTVNVASRM 1080
ESTGVMGNIQ VVEETQVILR EYGFRFVRRG PIFVKGKGEL LTFFLKGRDR PAAFPNGSSV 1140
TLPHQVVDNP 1150 
Gene Ontology
 GO:0005929; C:cilium; IDA:MGI.
 GO:0005886; C:plasma membrane; TAS:MGI.
 GO:0004016; F:adenylate cyclase activity; TAS:MGI.
 GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
 GO:0007190; P:activation of adenylate cyclase activity; TAS:MGI.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro. 
Interpro
 IPR001054; A/G_cyclase.
 IPR018297; A/G_cyclase_CS. 
Pfam
 PF00211; Guanylate_cyc 
SMART
 SM00044; CYCc 
PROSITE
 PS00452; GUANYLATE_CYCLASE_1
 PS50125; GUANYLATE_CYCLASE_2 
PRINTS