CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043254
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 cAMP-regulated phosphoprotein 19 
Protein Synonyms/Alias
  
Gene Name
 ARPP19 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
61RYPHLGQKPGGSDFLacetylation[1]
61RYPHLGQKPGGSDFLubiquitination[1]
77KRLQKGQKYFDSGDYacetylation[1, 2]
77KRLQKGQKYFDSGDYubiquitination[1, 3, 4, 5]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [5] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 131 AA 
Protein Sequence
MSAEVPEAAS AEEQKSEHNM LPWSLQPSIP NSLEEMEDKV TSPEKAEEAK LKARYPHLGQ 60
KPGGSDFLRK RLQKGQKYFD SGDYNMAKAK MKNKQLPTAA PDKTEVTGDH IPTPQDLPQR 120
KPSLVASKLA G 131 
Gene Ontology
  
Interpro
 IPR006760; Endosulphine. 
Pfam
 PF04667; Endosulfine 
SMART
  
PROSITE
  
PRINTS