UniProt Accession

 RDH13_HUMAN; Q8NBN7; Q6UX79; Q96G88 

Genbank Protein ID

 AY358473; AK075392; AC011476; BC009881 

Genbank Nucleotide ID

 AAQ88837.1; BAC11591.1; AAH09881.1 

Protein Name

 Retinol dehydrogenase 13 

Protein Synonyms/Alias

  

Gene Name

 RDH13 

Gene Synonyms/Alias

 PSEC0082; UNQ736/PRO1430 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
33	TGGACPSKATIPGKT	ubiquitination	[1]
102	HLDLASLKSIREFAA	ubiquitination	[1, 2, 3]
212	LAIVLFTKELSRRLQ	ubiquitination	[1]
292	GKYFDGLKQKAPAPE	ubiquitination	[1]
294	YFDGLKQKAPAPEAE	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Does not exhibit retinol dehydrogenase (RDH) activity in vitro. 

Sequence Annotation

 NP_BIND 45 51 NAD or NADP (By similarity).
 ACT_SITE 200 200 Proton acceptor (By similarity).
 BINDING 174 174 Substrate (By similarity).  

Keyword

 Alternative splicing; Complete proteome; NADP; Oxidoreductase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 331 AA 

Protein Sequence

Gene Ontology

 GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. 

Interpro

 IPR002198; DH_sc/Rdtase_SDR.
 IPR002347; Glc/ribitol_DH.
 IPR016040; NAD(P)-bd_dom.
 IPR020904; Sc_DH/Rdtase_CS. 

Pfam

 PF00106; adh_short 

SMART

  

PROSITE

 PS00061; ADH_SHORT 

PRINTS

 PR00081; GDHRDH.
 PR00080; SDRFAMILY.