CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-045303
UniProt Accession
M0QYX3_HUMAN
;
M0QYX3
Genbank Protein ID
AC011495
Genbank Nucleotide ID
Protein Name
Interferon regulatory factor 3
Protein Synonyms/Alias
Gene Name
IRF3
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Homo sapiens (Human)
NCBI Taxa ID
9606
Lysine Modification
Position
Peptide
Type
References
70
AYVPGRD
K
PDLPTWK
ubiquitination
[1]
Reference
[1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [
PMID: 21890473
]
Functional Description
Sequence Annotation
Keyword
Complete proteome; Reference proteome.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
191 AA
Protein Sequence
MGTPKPRILP WLVSQLDLGQ LEGVAWVNKS RTRFRIPWKH GLRQDAQQED FGIFQAWAEA 60
TGAYVPGRDK PDLPTWKRNF RSALNRKEGL RLAEDRSKDP HDPHKIYEFV NSGVGDFSQP 120
DTSPDTNGGG STSDTQEDIL DELLGNMVLA PLPDPGPPSL AVAPEPCPQP LRSPSLDNPT 180
PFPNLGPSEN P 191
Gene Ontology
GO:0000975
; F:regulatory region DNA binding; IEA:InterPro.
GO:0003700
; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
Interpro
IPR019817
; Interferon_reg_fac_CS.
IPR001346
; Interferon_reg_fact_DNA-bd_dom.
IPR011991
; WHTH_DNA-bd_dom.
Pfam
PF00605
; IRF
SMART
SM00348
; IRF
PROSITE
PS00601
; IRF_1
PS51507
; IRF_2
PRINTS
PR00267
; INTFRNREGFCT.