CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025411
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 4 
Protein Synonyms/Alias
  
Gene Name
 Hsd3b4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
49KQEEELSKLQTKTKVubiquitination[1]
60KTKVTVLKGDILDAQubiquitination[1]
70ILDAQCLKRACQGMSubiquitination[1]
164YSKKMAEKAVLAANGubiquitination[1]
245RSLQDPKKSPSIQGQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Isomerase; Oxidoreductase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 373 AA 
Protein Sequence
MPGWSCLVTG AGGFLGQRIV RMLVQEEELQ EIRALFRTFG RKQEEELSKL QTKTKVTVLK 60
GDILDAQCLK RACQGMSAVI HTAAAIDPLG AASRQTILDV NLKGTQLLLD ACVEANVPTF 120
IYSSSVLVAG PNSYKEIILN AHEEEHHEST WSNPYPYSKK MAEKAVLAAN GSILKNGGTL 180
HTCALRLSFI YGEECQVTST TVKTALKNNS IIKKNATFSI ANPVYVGNAA WAHILAARSL 240
QDPKKSPSIQ GQFYYITDDT PHQSYDDLKC TLSKEWGLRL DTSWSLPLPL LYWLAFLLET 300
VSFLLRPVYN YRPPFNRLLI TVLNSVFTFS YKKAQRDLGY EPLVSWEEAK QKTSEWIGTL 360
VMQHREIGNK KSQ 373 
Gene Ontology
 GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
 GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
 GO:0006694; P:steroid biosynthetic process; IEA:InterPro. 
Interpro
 IPR002225; 3Beta_OHSteriod_DH/Estase.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF01073; 3Beta_HSD 
SMART
  
PROSITE
  
PRINTS