CPLM-017607

CPLM 1.0 - Compendium of Protein Lysine Modification

Tag

Content

CPLM ID

CPLM-017607

UniProt Accession

CAMKV_HUMAN; Q8NCB2; A6NFD4; Q6FIB8; Q8NBS8; Q8NC85; Q8NDU4; Q8WTT8; Q9BQC9; Q9H0Q5

Genbank Protein ID

AK074856; AK074899; AK075294; AL136697; CR533508; AL833943; AC105935; CH471055; BC000497; BC001921; BC005828; BC017363; BC019256

Genbank Nucleotide ID

BAC11248.1; BAC11278.1; BAC11528.1; CAB66632.1; CAG38539.1; CAD38798.2; EAW65027.1; AAH00497.1; AAH01921.1; AAH05828.1; AAH17363.1; AAH19256.1

Protein Name

CaM kinase-like vesicle-associated protein

Protein Synonyms/Alias

Gene Name

CAMKV

Gene Synonyms/Alias

Created Date

July 27, 2013

Organism

Homo sapiens (Human)

NCBI Taxa ID

9606

Lysine Modification

Position	Peptide	Type	References
65	RDGRKVRKAAKNEIG	ubiquitination	[1]

Reference

[1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]

Functional Description

Does not appear to have detectable kinase activity.

Sequence Annotation

DOMAIN 24 286 Protein kinase.
MOD_RES 154 154 Phosphotyrosine (By similarity).
MOD_RES 403 403 Phosphothreonine (By similarity).
MOD_RES 435 435 Phosphothreonine (By similarity).
MOD_RES 438 438 Phosphothreonine (By similarity).
MOD_RES 441 441 Phosphoserine (By similarity).
MOD_RES 459 459 Phosphothreonine (By similarity).

Keyword

Alternative splicing; Calmodulin-binding; Cell membrane; Complete proteome; Cytoplasmic vesicle; Membrane; Phosphoprotein; Polymorphism; Reference proteome.

Sequence Source

UniProt (SWISSPROT/TrEMBL); GenBank; EMBL

Protein Length

501 AA

Protein Sequence

MPFGCVTLGD KKNYNQPSEV TDRYDLGQVI KTEEFCEIFR AKDKTTGKLH TCKKFQKRDG 60
RKVRKAAKNE IGILKMVKHP NILQLVDVFV TRKEYFIFLE LATGREVFDW ILDQGYYSER 120
DTSNVVRQVL EAVAYLHSLK IVHRNLKLEN LVYYNRLKNS KIVISDFHLA KLENGLIKEP 180
CGTPEYLAPE VVGRQRYGRP VDCWAIGVIM YILLSGNPPF YEEVEEDDYE NHDKNLFRKI 240
LAGDYEFDSP YWDDISQAAK DLVTRLMEVE QDQRITAEEA ISHEWISGNA ASDKNIKDGV 300
CAQIEKNFAR AKWKKAVRVT TLMKRLRAPE QSSTAAAQSA SATDTATPGA AGGATAAAAS 360
GATSAPEGDA ARAAKSDNVA PADRSATPAT DGSATPATDG SVTPATDGSI TPATDGSVTP 420
ATDRSATPAT DGRATPATEE STVPTTQSSA MLATKAAATP EPAMAQPDST APEGATGQAP 480
PSSKGEEAAG YAQESQREEA S 501

Gene Ontology

GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.
GO:0004672; F:protein kinase activity; IEA:InterPro.

Interpro

IPR020636; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009; Kinase-like_dom.
IPR000719; Prot_kinase_cat_dom.
IPR002290; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00069; Pkinase

SMART

SM00220; S_TKc

PROSITE

PS50011; PROTEIN_KINASE_DOM

PRINTS