CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039430
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Structural maintenance of chromosomes protein 
Protein Synonyms/Alias
  
Gene Name
 Smc4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
944DSVCRTEKEIKDTEKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1286 AA 
Protein Sequence
MRRKGTKPST ACHQEEGPPP SEDGALSEGE KEQPDCEVDS AAAAETPGEE LDSRSLEEIL 60
NSIPPPPPPA MASEAGAPRL MITHIVNQNF KSYAGEKILG PFHKRFSCII GPNGSGKSNV 120
IDSMLFVFGY RAQKIRSKKL SVLIHNSDEH TDIQSCTVEV HFQKIIDKEG DDYDVLPNSN 180
FYVSRTAYRD NTSVYHISGK KRTFKDVGNL LRSHGIDLDH NRFLILQGEV EQIAMMKPKG 240
QTEHDEGMLE YLEDIIGCGR LNEPIKVLCR RVEILNEHRG EKLNRVKMVE KEKDALEGEK 300
NIAIEFLTLE NEIFKKKNHI CQYYIYDLQN RIAEMKTQKE KIHEDTKEIT EKSNVLSNEM 360
KAKNSAVKDI EKKLNKVTKF IEQNKEKFTQ LDLEDVQVRE KLKHATSKAK KLEKQLQKDK 420
EKVEELKSIP AKSKNVINET TTRNNSLEKE REKEEKKLKE VMDSLKQETQ GLQKEKEIQE 480
KELMGFNKSV NEARSKMEVA QSELDIYLSR HNTAVSQLSK AKDALITASE TLKERKAAIK 540
DINTKLPQAQ QELKEKEKEL QKLTQEEINL KSLVHDLFQK VEEAKSSLAT NRSRGKVLDA 600
IIQEKKSGRI PGIYGRLGDL GAIDEKYDIA ISSCCHALDY IVVDSIDTAQ ECVNFLKKHN 660
IGVATFIGLD KMAVWAQKMN KIQTPENTPR LFDLVKVKNE EIRQAFYFAL RDTLVANNLD 720
QATRVAYQRD RRWRVVTLQG QIIEQSGTMT GGGSKVMRGR MGSSVVDEIS VEEVNKMECQ 780
LERHSKQAAQ VQEQKVQHEE AIVKLKQSER EMRNTLEKFT ASIQGLSEQE EYLCVQIKEL 840
EANVLTTAPD KKQQKLLEEN VNVFKKEYDA VAEKAGKVEA EIKRLHDTII DINNRKLKAQ 900
QNKLDTINKQ LDECASAITK AQVAIKTADR NLKKAQDSVC RTEKEIKDTE KEINDLKTEL 960
KNIEDNAEEV IKNTKDAEKS LPEIQKEHRA LLQELKVIQD NEHALQKDAL SIKLKLEQID 1020
GHISEHNSKI KYWQKEISKI KLHPVEDNPV ETVSVLSQED LEAIKSPDSI TNQIALLEAQ 1080
CREMKPNLGA IAEYKKKEEL YLQRVGELDK ITSERDNFRQ AYEDLRKQRL NEFMAGFYVI 1140
TNKLKENYQM LTLGGDAELE LVDSLDPFSE GIMFSVRPPK KSWKKIFNLS GGEKTLSSLA 1200
LVFALHHYKP TPLYFMDEID AALDFKNVSI VAFYIYEQTK NAQFIIISLR NNMFEISDRL 1260
IGIYKTYNIT KSVAVNPKEI ASKGLC 1286 
Gene Ontology
 GO:0000796; C:condensin complex; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0006310; P:DNA recombination; IEA:InterPro.
 GO:0006281; P:DNA repair; IEA:InterPro.
 GO:0051383; P:kinetochore organization; IEA:Compara.
 GO:0010032; P:meiotic chromosome condensation; IEA:Compara.
 GO:0045132; P:meiotic chromosome segregation; IEA:Compara.
 GO:0007076; P:mitotic chromosome condensation; IEA:Compara.
 GO:0007062; P:sister chromatid cohesion; IEA:InterPro. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR003395; RecF/RecN/SMC.
 IPR024704; SMC.
 IPR010935; SMC_hinge. 
Pfam
 PF06470; SMC_hinge
 PF02463; SMC_N 
SMART
 SM00968; SMC_hinge 
PROSITE
  
PRINTS