CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036988
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Long-chain-fatty-acid--CoA ligase 6 
Protein Synonyms/Alias
  
Gene Name
 ACSL6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
531WLPAGTLKIIDRKKHubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 677 AA 
Protein Sequence
MQTQEILRIL RLPELGDLGQ FFRSLSATTL DSGGARRSVI GSGPQLLTHY YDDARTMYQV 60
FRRGLSISGN GPCLGFRKPK QPYQWLSYQE VADRAEFLGS GLLQHNCKAC TDQFIGVFAQ 120
NRPEWIIVEL ACYTYSMVVV PLYDTLGPGA IRYIINTGLS CQEGASATAS TQADISTVIV 180
DKPQKAVLLL EHVERKETPG LKLIILMDPF EEALKERGQK CGVVIKSMQA VEDCGQENHQ 240
APVPPQPDDL SIVCFTSGTT GNPKGAMLTH GNVVADFSGF LKVTEKVIFP RQDDVLISFL 300
PLAHMFERVI QSVVYCHGGR VGFFQGDIRL LSDDMKALCP TIFPVVPRLL NRMYDKIFSQ 360
ANTPLKRWLL EFAAKRKQAE VRSGIIRNDS IWDELFFNKI QASLGGCVRM IVTGAAPASP 420
TVLGFLRAAL GCQVYEGYGQ TECTAGCTFT TPGDWTSGHV GAPLPCNHIK LVDVEELNYW 480
ACKGEGEICV RGPNVFKGYL KDPDRTKEAL DSDGWLHTGD IGKWLPAGTL KIIDRKKHIF 540
KLAQGEYVAP EKIENIYIRS QPVAQIYVHG DSLKAFLVGI VVPDPEVMPS WAQKRGIEGT 600
YADLCTNKDL KKAILEDMVR LGKESGLHSF EQVKAIHIHS DMFSVQNGLL TPTLKAKRPE 660
LREYFKKQIE ELYSISM 677 
Gene Ontology
 GO:0003824; F:catalytic activity; IEA:InterPro. 
Interpro
 IPR020845; AMP-binding_CS.
 IPR000873; AMP-dep_Synth/Lig. 
Pfam
 PF00501; AMP-binding 
SMART
  
PROSITE
 PS00455; AMP_BINDING 
PRINTS