CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039239
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Neb 
Protein Synonyms/Alias
  
Gene Name
 Neb 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
82SVDVMRVKNAQNLLNacetylation[1]
291NDVIQARKAYDLQSDacetylation[1]
402NALNVSHKLYREGWDacetylation[1]
438REIASDYKYKLDHEKacetylation[1]
487QWAKWKTKFQSPVDMacetylation[1]
621DWNAIKSKYTLTETPacetylation[1]
861KYKETFNKAKGKYMFacetylation[1]
915YIPIVGAKHADLVNSacetylation[1]
925DLVNSELKYKETYEKacetylation[1]
1141IYKEAWDKVKATSYNacetylation[1]
1170KHLASRIKYREEYEKacetylation[1]
1177KYREEYEKFKALYTLacetylation[1]
1186KALYTLPKSVDDDPNacetylation[1]
1265QVNSHVRKVTDQISDacetylation[1]
1309YDLRNDIKYKAHVQKacetylation[1]
1362GKVAPTTKTVDLDRAacetylation[1]
1374DRALHAYKLQSENLYacetylation[1]
1458LYRELYHKLKDKIHTacetylation[1]
1668KYKIQYEKMKDKYTPacetylation[1]
1707TFQKTKGKYHTVKDAacetylation[1]
1712KGKYHTVKDALDIVYacetylation[1]
1900LRTTKVNKQISDILYacetylation[1]
1957NKSNCTIKPDAVHIKacetylation[1]
1979VNTNLDYKKQYEANKacetylation[1]
2113VHVKAVTKHVSDTNYacetylation[1]
2243KTPKYNPKDSQLYKTacetylation[1]
2252SQLYKTMKDANNLASacetylation[1]
2299LASSYQYKKNYEKSKacetylation[1]
2775QRHISTVKYHEDFEKacetylation[1]
2782KYHEDFEKHKGCFTPacetylation[1]
2953SHPSTAGKIFRAIYDacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 3009 AA 
Protein Sequence
GIYNTPLDMM SIVQAKKCQV LVSDVDYRNY LHQWTCLPDQ NDVIQAKKAY ELQSDNVYKS 60
DLEWMKGIGW LTEGSVDVMR VKNAQNLLNE RLYRIKPEAY KFTSIVDTPE VILAKTNALQ 120
ISEPLYRDAW DKEKANVNVP ADTPVMLQSK LNAIQISNKQ YQKAWEDVKM TGYDIRADAI 180
GIQHAKASRD IASDYLYKTA YEKQKGHYIG CPSAKEDPKL VWAANVLKMQ NDRLYKKAYN 240
DHKAKISIPG DMVSINAAKE GQALASNVDY RQYLHQWSCF PDQNDVIQAR KAYDLQSDAI 300
YKADLEWLRG IGWMPEGSPE VLRVKNAQEI LCDSVYRTPV VKLKYTSIVD TPEVVLAKSN 360
AENISIPKYR EVWDKDKTSI HIMPDTPEIN LARANALNVS HKLYREGWDE VKMSCDVRLD 420
AIPIQAAKAS REIASDYKYK LDHEKQKGHY VGTLTARDDN KIRWALIAGK IQNEREYRLQ 480
WAKWKTKFQS PVDMLSILHS KKCQTLVSDI DYRNYLHQWT CMPDQNDVIQ AKKAYELQSD 540
AVYKADLEWL RGIGWMPNDS VSVNHAKHAA DIFSEKKYRT KIETLNFTPV DDRVDYVTAK 600
QSSEIRDDIK YRKDWNAIKS KYTLTETPLL HTAQEAARIL DQYLYKEGWE KQKATGYILP 660
PDAVPFVHAH HSSDVQSELK YKAEHVKQRG HYVGVPTMRD DPKLVWFEHA GQIQNDRLYK 720
ESYHKSKAKI NIPADMVSVV AAKEGQSLVS DIDYRQYLHQ WTCHPDQNDV IQAKIAYDLQ 780
SDNVYKADLE WLRGIGWIPL DSVDHVRVTK NQEMVNQIKY KKDALDNYPN FTSVVDPPEI 840
VLAKINSVNQ SDVKYKETFN KAKGKYMFSP DTPYISHSKD MGKLYSTILY KGAWEGTKAY 900
GYTLDERYIP IVGAKHADLV NSELKYKETY EKQKGHYLAG KEISEFPGVV HCLDFQQMRS 960
ALNYRKDYED TKANVHIPND MMNHVLAKRC QYILSDLEYR HYFHQWTSLP EEPNVIRARN 1020
AQEILSDNVY KDDLNWLKGI GCYVWDTPQI LHAKKSYDLQ SQLQYTAASK ENLQNYNLVT 1080
DTPVYVTALQ SGINASEVKY KENYHQIKDK YTTVLETADY DRTKNLKSLY SSNIYKEAWD 1140
KVKATSYNLP TSTLSLTHAK NQKHLASRIK YREEYEKFKA LYTLPKSVDD DPNTARCLRV 1200
GKLNIDRLYR SVYEKNKMKI NIVPDMVEMV TAKDSQKKVS EIDYRLHLHE WICHPDLQVN 1260
SHVRKVTDQI SDIVYKDDLT WLKGIGCYVW DTPEILHAKH AYDLRNDIKY KAHVQKTRND 1320
YKLVTDTPVY VQAVKSGKQL SDAVYHYDYI HSVRGKVAPT TKTVDLDRAL HAYKLQSENL 1380
YKKGLRFLPT GYRLPVDTPH FNHTKDTRYM SSYFKYKEAY EHIKANGYTL GPKDVPFVHV 1440
RRVNNVTSER LYRELYHKLK DKIHTTPDTP EIRQVKKTQE AVSELIYKSD FFKMQGHMIS 1500
LPYTPQVLHC RYVGDITSDI KYKEDLQILK GLGCFLYDTP DMVRSRHLRK LWSNYLYTDK 1560
ARKMRDKYKV VLDTPEYRKV QELKTHLSEL VYRASGKKQK SIFTSVPDTP DLLRAKRGQK 1620
LQSQYLYVEL ATKERPHHHA GNQTTALQHA KDVKDMVSEK KYKIQYEKMK DKYTPVADTP 1680
ILIRAKRAYW NASDLRYKET FQKTKGKYHT VKDALDIVYH RKVTDDISKV KYKENYMSQL 1740
GIWSSIPDRP EHFHHRAVTD AVSDVKYKED LTWLKGIGCY AYDTPDLALA EQNKTLYSKY 1800
KYKEVFERTK SNFKYVADCP INRHFKYATQ LMNEKKYRAD YEQRKDKYHL VVDEPRHLLA 1860
KTAGDQISQI KYRKKYEKSK DKFTSVVDTP EHLRTTKVNK QISDILYKLE YNKARPRGYT 1920
TIHDTPMLLH VRKVKDEVSD LKYKEVYQRN KSNCTIKPDA VHIKAAKDAY KVNTNLDYKK 1980
QYEANKAYWK WTPDRPDFIQ AAKSSLQQSD FEYKLDREFL KGCKLSVTDD KDMVLALRNS 2040
LIESDLKYKE KHVKERGTCH AVPDTPQILL AKTVSNLVSE NKYKDHVKKH LAQGSYTTLP 2100
ETRDTVHVKA VTKHVSDTNY KKKFVKEKGK SNYSIMQEPP EVKHAMDVAK KQSDVAYKKD 2160
AKENLHYTTV ADRPDIKKAT QAAKQASEVE YRAKHRKEGS HGLSMLGRPD IEMAKKAAKL 2220
SSQVKYRENF DKEKGKTPKY NPKDSQLYKT MKDANNLASE VKYKADLKKL HKPVTDMKES 2280
LIMHHVLNTS QLASSYQYKK NYEKSKGHYH TIPDNLEQLH LKEATELQSI VKYKEKYEKE 2340
RGKPMLDFET PTYITAKESQ QMQSGKEYRK DYEESIKGRN LTGLEVTPAL LHVRHATKIA 2400
SEKEYRKDLE ESIRGRGLTE MEDTPEMLRA KNATQILNEK EYKRDLELEV KGRGLNAMAN 2460
ETPDFMRARN ATDIASQIKY KQSAEMEKAN FTSVVDTPEI IHAQQVKNLS SQKKYKEDAE 2520
KSMSYYETVL DTPEMQRVRE NQKNFSLLQY QCDLKNSKGK ITVVQDTPEI LRVKENQKNF 2580
SSVLYKEDVS PGTAIGKTPE MLRVKQTQDH ISSVKYKEAI GQGTPIPDLP EVKRVKETQK 2640
HISSVMYKEN LGTGIPTTVT PEIERVKRNQ ENFSSVLYKE NMGKGTPLPV TPEMERVKHN 2700
QENISSVLYK ENVGKATPTP VTPEMQRVKR NQENISSVLY SDSFRKQIQG KAAYVLDTPE 2760
MRRVRETQRH ISTVKYHEDF EKHKGCFTPV VTDPITERVK KNTQDFSDIN YRGIQRKVVE 2820
IEQKRNDQDQ DTITGLRVWR TNPGSVFDYD PAEDNIQSRS LHMVNVQAQR RSRDQSRSAS 2880
ALSISGGEEK SEHSEAADQR LSTYSDGGAF FSATSTAYKH VKTTELPQQR SSSVATQQTT 2940
LSSIPSHPST AGKIFRAIYD YMAADADEVS FKDGDAIVNA QAIDEGWMYG TVQRTGRTGM 3000
LPANYVEAI 3009 
Gene Ontology
 GO:0030016; C:myofibril; IDA:RGD. 
Interpro
 IPR013998; Nebulin.
 IPR000900; Nebulin_35r-motif.
 IPR001452; SH3_domain. 
Pfam
 PF00880; Nebulin
 PF00018; SH3_1 
SMART
 SM00227; NEBU
 SM00326; SH3 
PROSITE
 PS51216; NEBULIN
 PS50002; SH3 
PRINTS
 PR00510; NEBULIN.