UniProt Accession

 E7EV84_HUMAN; E7EV84 

Genbank Protein ID

 AC016889 

Genbank Nucleotide ID

  

Protein Name

 Beclin-1 

Protein Synonyms/Alias

  

Gene Name

 BECN1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
26	QRCSQPLKLDTSFKI	ubiquitination	[1]
32	LKLDTSFKILDRVTI	ubiquitination	[2]
130	EDVEKNRKIVAENLE	ubiquitination	[1]
138	IVAENLEKVQAEAER	ubiquitination	[1]
161	QREYSEFKRQQLELD	ubiquitination	[1]
172	LELDDELKSVENQMR	ubiquitination	[1]
187	YAQTQLDKLKKTNVF	ubiquitination	[1]
190	TQLDKLKKTNVFNAT	ubiquitination	[1]
248	LANKMGLKFQRYRLV	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 279 AA 

Protein Sequence

Gene Ontology

 GO:0006914; P:autophagy; IEA:InterPro. 

Interpro

 IPR007243; Beclin_fam. 

Pfam

 PF04111; APG6 

SMART

  

PROSITE

  

PRINTS