CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032690
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytosol aminopeptidase, putative 
Protein Synonyms/Alias
  
Gene Name
 TGVEG_084080 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
168VVLPTCQKVCPSAEGacetylation[1]
459YAGLWSNKECLASSIacetylation[1, 2]
Reference
 [1] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842]
 [2] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907] 
Functional Description
  
Sequence Annotation
  
Keyword
 Aminopeptidase; Complete proteome; Hydrolase; Protease; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 563 AA 
Protein Sequence
MSRVPAPLTV VKTDPTAIPF VGCQPAKKVR MEAVDISEAE KYSGDLIVFS VLAPGCFHDA 60
PNASQPQKGP IALPELAQKF DDAVGQGMLK DAVEAADFKA KMGSQVFVRL PSKSAPAVKH 120
LAALGFGSIA EVTPSAVTKA AAAFASMLLR GSGEKAKTVA VVLPTCQKVC PSAEGQRKTR 180
EMKERVVTSF LETLLVELQP DLRFKGDRED GKHSGPQVEK LTLFTDDVEA VNRAIARAKV 240
VAPGVYFAQE LVNAPANYCN PVTLARAAVE MAKEAGLEAE VLQQDDIEKL KMGCYLAVAK 300
GSLFPPQFIH LTYKSSNPKR RVAFVGKGIC FDAGGYNLKT GGAQIELMKF DMGGAAAVLG 360
AARALGELKP ENVEVHFLVA ACENMISAKS YRPGDVITAS NGKTVEVGNT DAEGRLTLAD 420
ALVYAEKTVK ADTIVDVATL TGAVIVALGY KYAGLWSNKE CLASSILKSA ENSGEYMWHM 480
PLAKDYAEAL DSKCADMNNV GGKGKGGSII AAVFLNKFIE QASWAHIDIA GTAWDMKTSM 540
ATGFGVRTLV EYIMDISAQT KEN 563 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
 GO:0030145; F:manganese ion binding; IEA:InterPro.
 GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR011356; Leucine_aapep/pepB.
 IPR000819; Peptidase_M17_C.
 IPR023042; Peptidase_M17_leu_NH2_pept.
 IPR008283; Peptidase_M17_N. 
Pfam
 PF00883; Peptidase_M17
 PF02789; Peptidase_M17_N 
SMART
  
PROSITE
 PS00631; CYTOSOL_AP 
PRINTS
 PR00481; LAMNOPPTDASE.