UniProt Accession

 Q6MG98_RAT; Q6MG98 

Genbank Protein ID

 AABR06099861; BC098677; BX883043; CH473988 

Genbank Nucleotide ID

 AAH98677.1; CAE83948.1; EDL96796.1 

Protein Name

 Histocompatibility 2, class II antigen E alpha 

Protein Synonyms/Alias

 Protein RT1-Da; RCG60548; RT1 class II, D alpha 

Gene Name

 RT1-Da 

Gene Synonyms/Alias

 Arrb2-ps; H2-Ea; Hla-dma; Hla-dmb; Psmb9; RT1-Ba; RT1-Bb; RT1-Db1; RT1-Db2; RT1-DOb; Tap1; Tap2; Tesb; rCG_60548 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
100	ANLDIMIKRSNNTPD	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Immunity; Membrane; MHC II; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 255 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0031902; C:late endosome membrane; IEA:Compara.
 GO:0005765; C:lysosomal membrane; IEA:Compara.
 GO:0042613; C:MHC class II protein complex; IEA:UniProtKB-KW.
 GO:0002504; P:antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; IEA:UniProtKB-KW.
 GO:0006955; P:immune response; IEA:InterPro. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003006; Ig/MHC_CS.
 IPR003597; Ig_C1-set.
 IPR011162; MHC_I/II-like_Ag-recog.
 IPR014745; MHC_II_a/b_N.
 IPR001003; MHC_II_a_N. 

Pfam

 PF07654; C1-set
 PF00993; MHC_II_alpha 

SMART

 SM00407; IGc1
 SM00920; MHC_II_alpha 

PROSITE

 PS50835; IG_LIKE
 PS00290; IG_MHC 

PRINTS