UniProt Accession

 TPPP3_RAT; Q5PPN5 

Genbank Protein ID

 BC087585 

Genbank Nucleotide ID

 AAH87585.1 

Protein Name

 Tubulin polymerization-promoting protein family member 3 

Protein Synonyms/Alias

  

Gene Name

 Tppp3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
24	FAIHGDPKASGQEMN	acetylation	[1]
33	SGQEMNGKNWAKLCK	acetylation	[1]
76	VINYEEFKKALEELA	acetylation	[1]
77	INYEEFKKALEELAT	ubiquitination	[2]
130	DRLTDTSKYTGSHKE	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 

Functional Description

 Binds tubulin and has microtubule bundling activity. May play a role in cell proliferation and mitosis (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 176 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0015631; F:tubulin binding; ISS:UniProtKB.
 GO:0001578; P:microtubule bundle formation; ISS:UniProtKB. 

Interpro

 IPR008907; P25-alpha. 

Pfam

 PF05517; p25-alpha 

SMART

  

PROSITE

  

PRINTS