CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007501
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Bud site selection protein 6 
Protein Synonyms/Alias
 Actin-interacting protein 3 
Gene Name
 BUD6 
Gene Synonyms/Alias
 AIP3; YLR319C; L8543.5 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
682LCCEEQEKNPSRSKSubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Not essential for mitotic growth but is necessary for normal morphogenesis. Involved in the organization and/or function of the actin cytoskeleton. 
Sequence Annotation
 MOD_RES 12 12 Phosphothreonine.
 MOD_RES 233 233 Phosphoserine.
 MOD_RES 327 327 Phosphoserine.
 MOD_RES 342 342 Phosphoserine.  
Keyword
 3D-structure; Coiled coil; Complete proteome; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 788 AA 
Protein Sequence
MKMAVDDPTY GTPKIKRTAS SSSSIETTVT KLLMSTKHLL QVLTQWSKGT TSGRLVSDAY 60
VQLGNDFKVV SKFFMHAKVD MSDVGDVPMA LRRVLEVTLR EPPSDETLNK HLPKIREIIV 120
TLLDKLKVKQ AILKNMQQEH RISVKSHHQQ NPSFTSNLSL GSEGTREGTP LSSRKSSIVR 180
DQRQSDSVEN SYGEKVNSTS TGTPSAQSAE ATLTKPRTNI KQNLKSNNAP NASDDDDALS 240
QLKKGTNLQR RASKRYSAYH MAKLTNQSTT EAAAAAGLMT TPSPSMLHLE ETVRKSKLYG 300
NNNNDDDRNI NSAENKGKSI DDVSKASPLA KTPLPIENVR ASPRRLSSVV TTSPDKAMNG 360
TCPVFLRIGD KTKKCHVQLP TTKNALRLLF IERFAYSPGA NSFPDIYIMD PQYGVFYELE 420
ELNLLDIKEG FVIELKLEEN PNNTIKEFID TVKMEISNSQ NDIIRHLKEM SFGSAISGKQ 480
TEVLPQPGLE ANKHDLVGQN KKDDDKTIKD IQYELGKIKQ VHNINRSNIN ETIFNILRKV 540
DNFKSLSFSA KNSSNRMYME KSQTELGDLS DTLLSKVDDL QDVIEIMRKD VAERRSQPAK 600
KKLETVSKDL ENAQADVLKL QEFIDTEKPH WKKTWEAELD KVCEEQQFLT LQEELILDLK 660
EDLGKALETF DLIKLCCEEQ EKNPSRSKSN PILPIMRPGT FNQVREQVMV AVQSLNPDHD 720
SRVEAIDKAE KMWEMERKLK ASNEFDDELE NFVGNSNLKK SGGFEEVERI RKQKDEANLR 780
AYFGPGFT 788 
Gene Ontology
 GO:0005935; C:cellular bud neck; IDA:SGD.
 GO:0005934; C:cellular bud tip; IDA:SGD.
 GO:0000131; C:incipient cellular bud site; IDA:SGD.
 GO:0043332; C:mating projection tip; IDA:SGD.
 GO:0000133; C:polarisome; IDA:SGD.
 GO:0005816; C:spindle pole body; IDA:SGD.
 GO:0003779; F:actin binding; IDA:SGD.
 GO:0005519; F:cytoskeletal regulatory protein binding; IDA:SGD.
 GO:0051017; P:actin filament bundle assembly; IMP:SGD.
 GO:0030953; P:astral microtubule organization; IMP:SGD.
 GO:0007121; P:bipolar cellular bud site selection; IMP:SGD.
 GO:0034652; P:extrachromosomal circular DNA localization involved in cell aging; IMP:SGD.
 GO:0090338; P:positive regulation of formin-nucleated actin cable assembly; IDA:SGD. 
Interpro
 IPR005613; AIP3.
 IPR022782; AIP3_C. 
Pfam
 PF03915; AIP3 
SMART
 SM00806; AIP3 
PROSITE
  
PRINTS