| Tag | Content |
|---|
| CPLM ID | CPLM-024340 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Patatin-like phospholipase domain-containing protein 7 |
Protein Synonyms/Alias | |
Gene Name | Pnpla7 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 691 | VRDSELAKLPAGALT | ubiquitination | [1] | | 1207 | YRTLDFGKFDEICEV | ubiquitination | [1] | | 1234 | VRSGVLEKMLQDQQG | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Serine hydrolase, whose specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy (By similarity). |
Sequence Annotation | DOMAIN 950 1116 Patatin.
NP_BIND 170 297 cNMP 1.
NP_BIND 478 602 cNMP 2.
NP_BIND 598 718 cNMP 3.
MOTIF 981 985 GXSXG.
ACT_SITE 983 983 By similarity.
MOD_RES 379 379 Phosphoserine.
CARBOHYD 102 102 N-linked (GlcNAc...) (Potential).
CARBOHYD 401 401 N-linked (GlcNAc...) (Potential).
CARBOHYD 750 750 N-linked (GlcNAc...) (Potential).
CARBOHYD 1036 1036 N-linked (GlcNAc...) (Potential).
CARBOHYD 1255 1255 N-linked (GlcNAc...) (Potential). |
Keyword | Alternative splicing; Complete proteome; Endoplasmic reticulum; Glycoprotein; Hydrolase; Lysosome; Membrane; Microsome; Mitochondrion; Nucleus; Phosphoprotein; Reference proteome; Repeat; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1352 AA |
Protein Sequence | MQNEEDACLE AGYCLGTTLS SWRLHFMEEQ SQSTMLMGIG IGALLTLAFV GITFFFVYRR 60
VRRLRRAEPT PQYRFRKRDK VMFYGRKIMR KVTTLPHTLV GNTSAPRQRV RKRTKVLSLA 120
KRILRFKKEY PTLQPKEPPP SLLEADLTEF DVKNSHLPSE VLYMLKNVRV LGHFEKPLFL 180
ELCKHMVFVQ LQEGEHVFQP GEPDISIYVV QDGRLEVCIQ DADGTEVVVK EVLPGDSVHS 240
LLSILDVITG HTAPYKTVSA RAAVSSTVLW LPAAAFQGVF EKYPETLVRV VQIIMVRLQR 300
VTFLALHNYL GLTTELFNPE SQAIPLLSVA SVAGRAKRQM SYGPEEQLER SLRPSEFSSS 360
DHGSSCVTVS GPLLKRSCSV PLPSNHGEVD ELRQSQGSGS NTSAFQESHE GATSDLGMAY 420
NRARILPHSD EQLGNSLASK SKKSVVAETP SAIFHYSENF RDETGACGKT DAIFRAATKD 480
LLTLMKLDDP SLLDGRVAFL HVPAGTLVSK QGDQDVNILF VVSGMLHVYQ QKIDSLEDTC 540
LFLTHPGEMV GQLAVLTGEP LMFTIRANRD CSFLSISKAH FYEIMRKRPD VVLGVAHTVV 600
KRMSSFVRQI DFALDWMEVE AGRAIYRQGD KSDCTYIVLS GRLRSVIRKD DGKKRLAGEY 660
GRGDLVGVVE TLTHQARATT VHAVRDSELA KLPAGALTSI KRRYPQVVTR LIHLLGEKIL 720
GSLQQGSATG HQLGFNTASS KWDLGNPPGN LSTVAALPAS EDVPLTAFAL ELQHALSAIG 780
PVLLLTSDNI KQRLGSAALD SIHEYRLSSW LGQQEDIHRI VLYQADGTLT PWTQRCIRQA 840
DCILIVGLGE QEPAVGELEQ MLESTAVRAQ KQLILLHKED GPVPSRTVEW LNMRSWCSGH 900
LHLCCPRRVF SKRSLPKLVE MYTRVFQRPP DRHSDFSRLA RMLTGNAIAL VLGGGGARGC 960
AQVGILRALA ECGVPVDIIG GTSIGAFMGA LFAEERSYSQ TRIRAKQWAE GMTSMMKTIL 1020
DLTYPITSMF SGTGFNSSIS NIFKDRQIED LWLPYFAITT DITASAMRVH TDGSLWRYVR 1080
ASMSLSGYMP PLCDPKDGHL LMDGGYINNL PADVARSMGA KVVIAIDVGS RDETDLTNYG 1140
DALSGWWLLW KRWNPLATKV KVLNMAEIQT RLAYVCCVRQ LEMVKNSDYC EYLRPPIDSY 1200
RTLDFGKFDE ICEVGYQHGR TVFDIWVRSG VLEKMLQDQQ GTSKRKDCGV FTCPNSSFTD 1260
LAEIVSRIEP AKVAAVDDES DYQTEYEEEL PAIPKETYAD FQSTGIELDS DSEYEPSMLQ 1320
GPPSLTSPEQ SQDSFPWLPN QDDQGPRLEH PS 1352 |
Gene Ontology | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. GO:0006629; P:lipid metabolic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |