UniProt Accession

 RS12_YEAST; P48589; D6W362; Q02545 

Genbank Protein ID

 U37460; U01049; Z75277; U24143; BK006948 

Genbank Nucleotide ID

 AAA80546.1; AAA69926.1; CAA99700.1; AAA65439.1; DAA11128.1 

Protein Name

 40S ribosomal protein S12 

Protein Synonyms/Alias

  

Gene Name

 RPS12 

Gene Synonyms/Alias

 YOR369C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
85	LANDPENKVPLIKVA	acetylation	[1]
85	LANDPENKVPLIKVA	ubiquitination	[2, 3]
90	ENKVPLIKVADAKQL	acetylation	[1]
90	ENKVPLIKVADAKQL	ubiquitination	[2, 3]
95	LIKVADAKQLGEWAG	acetylation	[1, 4]
95	LIKVADAKQLGEWAG	ubiquitination	[2, 3]
105	GEWAGLGKIDREGNA	acetylation	[1]
105	GEWAGLGKIDREGNA	ubiquitination	[3]
114	DREGNARKVVGASVV	acetylation	[4]
114	DREGNARKVVGASVV	ubiquitination	[2, 3]
124	GASVVVVKNWGAETD	acetylation	[4]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [3] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [4] mChIP-KAT-MS, a method to map protein interactions and acetylation sites for lysine acetyltransferases.
 Mitchell L, Huard S, Cotrut M, Pourhanifeh-Lemeri R, Steunou AL, Hamza A, Lambert JP, Zhou H, Ning Z, Basu A, Côté J, Figeys DA, Baetz K.
 Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):E1641-50. [PMID: 23572591] 

Functional Description

  

Sequence Annotation

  

Keyword

 3D-structure; Complete proteome; Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 143 AA 

Protein Sequence

Gene Ontology

 GO:0022627; C:cytosolic small ribosomal subunit; IDA:SGD.
 GO:0003735; F:structural constituent of ribosome; IDA:SGD.
 GO:0002181; P:cytoplasmic translation; IC:SGD. 

Interpro

 IPR004038; Ribosomal_L7Ae/L30e/S12e/Gad45.
 IPR000530; Ribosomal_S12e. 

Pfam

 PF01248; Ribosomal_L7Ae 

SMART

  

PROSITE

 PS01189; RIBOSOMAL_S12E 

PRINTS

 PR00972; RIBSOMALS12E.