UniProt Accession

 E9PIY6_HUMAN; E9PIY6 

Genbank Protein ID

 AC090589 

Genbank Nucleotide ID

  

Protein Name

 ADP-ribosylation factor GTPase-activating protein 2 

Protein Synonyms/Alias

  

Gene Name

 ARFGAP2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
7	*MAAEPNKTEIQTLF	ubiquitination	[1]
15	TEIQTLFKRLRAVPT	ubiquitination	[1, 2]
24	LRAVPTNKACFDCGA	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Metal-binding; Reference proteome; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 327 AA 

Protein Sequence

Gene Ontology

 GO:0005794; C:Golgi apparatus; IDA:HPA.
 GO:0005886; C:plasma membrane; IDA:HPA.
 GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. 

Interpro

 IPR001164; ArfGAP. 

Pfam

 PF01412; ArfGap 

SMART

 SM00105; ArfGap 

PROSITE

 PS50115; ARFGAP 

PRINTS

 PR00405; REVINTRACTNG.