CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024864
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dihydrolipoamide acyltransferase, putative 
Protein Synonyms/Alias
  
Gene Name
 PFC0170c 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
82AAVDITSKYNGVLVKacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
  
Sequence Annotation
  
Keyword
 Acyltransferase; Complete proteome; Lipoyl; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 448 AA 
Protein Sequence
MFVKNVLNVL RRIEGKSFKG RHYLNTSAIH FKIVKCKLFD IGEGISEVEI TKWHKNEGDQ 60
VSEMESLLTV QSDKAAVDIT SKYNGVLVKK YLNENDMLKV GSYFCEIDTD DDIIERDEEE 120
VEKEENNKKE EDGESDLSLN DDISNNDYIK ASPGVKRKAK EYKVNLNKVG DYFNKVNISL 180
EDLELYYNNV VKNEYSNNIN NNDMDIIEEV SLKGIKLAMC KSMNESLQVP LFHLNEMCII 240
NNLIKMRKEY KEQQKNLQTK ETNITITCIL IKLISNVLKE FPILNSKFNF KTNTYTMYKN 300
HNISIAVDTP HGLLVPNIKN VQNKNILDIQ KDLLSLRDKA NNMQLDKSDI TNGTITVSNF 360
GAISGTFATP IVFDNQACII GIGKMEKKLL LKDESNNLNS LNDILVADTI NFTFGADHRY 420
IDGATLAQFS KMLKMNIENC ASLGPLLE 448 
Gene Ontology
 GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW. 
Interpro
 IPR003016; 2-oxoA_DH_lipoyl-BS.
 IPR001078; 2-oxoacid_DH_actylTfrase.
 IPR000089; Biotin_lipoyl.
 IPR023213; CAT-like_dom.
 IPR011053; Single_hybrid_motif. 
Pfam
 PF00198; 2-oxoacid_dh
 PF00364; Biotin_lipoyl 
SMART
  
PROSITE
 PS50968; BIOTINYL_LIPOYL
 PS00189; LIPOYL 
PRINTS