CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039335
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Sucrase-isomaltase, intestinal 
Protein Synonyms/Alias
  
Gene Name
 Si 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
171TGNRFRFKITDPNNKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1832 AA 
Protein Sequence
MAKKKFSALE ISLIVLFIIV TAIAIALVAV LATKVPAVEE IKSPTPTSNS TPTSTPTSTS 60
IPTSTSTPSP GKCPPEQGEP INERINCIPE QHPTKAICEE RGCCWRPWNN TVIPWCFFAD 120
NHGYNAESIT NENAGLKATL NRIPSPTLFG EDIKSVILTT QTQTGNRFRF KITDPNNKRY 180
EVPHQFVKEE TGIPAADTLY DVQVSENPFS IKVIRKSNNK VLFDTSVGPL VYSNQYLQIS 240
TRLPSEYIYG FGEHIHKRFR HDLYWKTWPI FTRDEIPGDN NHNLYGHQTF FMGIEDTSGK 300
SYGVFLMNSN AMEVFIQPTP IITYRVTGGI LDFYIFLGDT PEQVVQQYQE VHWPAMPAYW 360
NLGFQLSRWN YGSLDTVKEV VRRNREAGIP YDAQVTDIDY MEDKKDFTYD EVKFNGLPEF 420
AQDLHNHGQK YIIILDPAIS INKRANGAEY QTYVRGNEKN VWVNESDGTT PLIGEVWPGL 480
TVYPDFTNPQ TIEWWANECN LFHQQVEYDG LWIDMNEVSS FIQGSLKGCT SNLLNYPPFT 540
PGILDKVMYS KTLCMDAVQH WGKQYDVHSL YGYSMAIATE QAVERVFPNK RSFILTRSTF 600
AGSGRHANHW LGDNTASWEQ MEWSITGMLE FGIFGMPLVG ADICGFLADT TEELCRRWMQ 660
LGAFYPFSRN HNAEGYMEQD PAYFGQDTSR HYLTIRYTLL PFLYTLFYRA HMFGETVARP 720
FLYEFYDDTN SWIEDTQFLW GPALLITPVL RPGVENVSAY IPNATWYDYE TGIKRPWRKE 780
RINMYLPGDK IGLHLRGGYI IPTQEPDVTT TASRKNPLGL IVALDDNQAA KGELFWDDGE 840
SKDSIEKKMY ILYTFSVSNN ELVLNCTHSS YAEGTSLAFK TIKVLGLGED VRSITVGEND 900
QQMATHTNFT FDSTNKILSI TALNFNLGKS FIVRWSQTFS DNEKFTCYPD VGTVTEETCK 960
QRGCLWQPVS GLSNVPPCYF PPEHNPYTLT SIQPLPTGIT AELQLNPANA RIKLPSNPIS 1020
TLRVEVKYHK NDMLQFKIYD AQHKRYEVPV PLNIPDTPTS SNERLYDVEI KENPFGIQVR 1080
RRSSGKLIWD SSLPGFAFND QFIQISTRLP SNYLYGFGEV EHTAFKRDLN WHTWGMFTRD 1140
QPPGYKLNSY GFHPYYMALE NEGNAHGVLL LNSNGMDVTF QPTPALTYRT IGGILDFYMF 1200
LGPTPEIATR QYHEVIGFPV MPPYWALGFQ LCRYGYRNTS EIEQLYNDMV AANIPYDVQY 1260
TDINYMERQL DFTIGERFKT LPEFVDRIRK DGMKYIVILD PAISGNETQP YPAFERGIQK 1320
DVFVKWPNTN DICWAKVWPD LPNVTIDETI TEDEAVNASR AHVAFPDFFR NSTLEWWARE 1380
IYDFYNEKMK FDGLWIDMNE PSSFVNGTVT NKCRNDTLNY PPYFPESKLT KRGEGLHFRT 1440
MCMETEHILS DGSSVLHYDV HNLYGWSQVK PTLDALQNTT GLRGIVISRS TYPTAGRWGG 1500
HWLGDNYANW DNLEKSLIGM LEFNLFGIPY IGADICGFFN DSEYHLCTRW MQVGAFYPYS 1560
RNHNIQFTRR QDPVSWNETF AQMSKKVLEI RYTLLPYFYT QMHEAHAQGG TVIRPLMHEF 1620
FDDKETWEIY KQFLWGPAFM VTPVVEPFRT SVTGYVPKAR WFDYHTGEDI KLKGILHTFS 1680
APFDTINLHV RGGYILPCQE PARNTHLSRQ NYMKLIVAAD DNQMAQGTLF WDDGESIDTY 1740
ERGQYTSIQF NLNQTTLTST VLANGYKNKQ EMRLGSIHIW GKGTLRISNA NLIYGGSKHQ 1800
PPFTQEEAKE TLIFDLKNMN VTLDEPIQIT WS 1832 
Gene Ontology
 GO:0016020; C:membrane; IEA:Compara.
 GO:0030246; F:carbohydrate binding; IEA:InterPro.
 GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
 GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. 
Interpro
 IPR011013; Gal_mutarotase_SF_dom.
 IPR000322; Glyco_hydro_31.
 IPR025887; Glyco_hydro_31_N_dom.
 IPR017853; Glycoside_hydrolase_SF.
 IPR000519; P_trefoil.
 IPR017957; P_trefoil_CS. 
Pfam
 PF13802; Gal_mutarotas_2
 PF01055; Glyco_hydro_31
 PF00088; Trefoil 
SMART
 SM00018; PD 
PROSITE
 PS00129; GLYCOSYL_HYDROL_F31_1
 PS00707; GLYCOSYL_HYDROL_F31_2
 PS00025; P_TREFOIL_1
 PS51448; P_TREFOIL_2 
PRINTS