CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001415
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative hydrolase RBBP9 
Protein Synonyms/Alias
 B5T-overexpressed gene protein; Protein BOG; Retinoblastoma-binding protein 9; RBBP-9 
Gene Name
 Rbbp9 
Gene Synonyms/Alias
 Bog 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
124PWQWEKIKANCPHIVacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441
Functional Description
 May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1 (By similarity). 
Sequence Annotation
 REGION 56 70 Retinoblastoma protein binding
 ACT_SITE 75 75 Charge relay system (Potential).
 ACT_SITE 138 138 Charge relay system (Potential).
 ACT_SITE 165 165 Charge relay system (Potential).
 MOD_RES 49 49 Phosphothreonine; by CK2 (Potential).
 MOD_RES 135 135 Phosphoserine; by CK2 (Potential).  
Keyword
 Complete proteome; Cytoplasm; Direct protein sequencing; Hydrolase; Nucleus; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 186 AA 
Protein Sequence
MASPNKAVIV PGNGGGDVAT HGWYGWVKKG LEQIPGFQCL AKNMPDPITA RESIWLPFME 60
TELHCDEKTI IIGHSSGAIA AMRYAETHQV YALVLVSAYT SDLGDENERA SGYFSRPWQW 120
EKIKANCPHI VQFGSTDDPF LPWKEQQEVA DRLDAKLYKF TDRGHFQNTE FHELISVVKS 180
MLKGPE 186 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
 GO:0042127; P:regulation of cell proliferation; IEA:Compara. 
Interpro
 IPR010662; DUF1234_Hydrolase. 
Pfam
 PF06821; Ser_hydrolase 
SMART
  
PROSITE
  
PRINTS