UniProt Accession

 A2A7Y8_MOUSE; A2A7Y8 

Genbank Protein ID

 AL607066 

Genbank Nucleotide ID

  

Protein Name

 Mitofusin-2 

Protein Synonyms/Alias

  

Gene Name

 Mfn2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
30	EVNASPLKHFVTAKK	ubiquitination	[1]
84	DVKGYLSKVRGISEV	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 97 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0015630; C:microtubule cytoskeleton; IDA:MGI.
 GO:0005741; C:mitochondrial outer membrane; IEA:InterPro.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0001825; P:blastocyst formation; IMP:MGI.
 GO:0048593; P:camera-type eye morphogenesis; IMP:MGI.
 GO:0006184; P:GTP catabolic process; IEA:GOC.
 GO:0008053; P:mitochondrial fusion; IMP:MGI.
 GO:0007006; P:mitochondrial membrane organization; IEA:Compara.
 GO:0051646; P:mitochondrion localization; IEA:Compara.
 GO:0046580; P:negative regulation of Ras protein signal transduction; IEA:Compara.
 GO:0048662; P:negative regulation of smooth muscle cell proliferation; IEA:InterPro.
 GO:0006626; P:protein targeting to mitochondrion; IEA:Compara. 

Interpro

 IPR027089; Mitofusin-2.
 IPR027094; Mitofusin_fam. 

Pfam

  

SMART

  

PROSITE

  

PRINTS