CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041499
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Integrin, alpha 6, isoform CRA_a 
Protein Synonyms/Alias
 Protein Itga6 
Gene Name
 Itga6 
Gene Synonyms/Alias
 rCG_26750 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
271SGKGIVSKDDITFVSacetylation[1]
914KQIDDSRKFSLFSERacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Cell adhesion; Complete proteome; Integrin; Membrane; Receptor; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1073 AA 
Protein Sequence
MAVAGQLCLL YLSAGLLARL STAFNLDTRE DNVIRKSGDP GSLFGFSLAM HWQLQPEDKR 60
LLLVGAPRAE ALPLQKANRT GGLYSCDITS RGPCTRIVFD NDADPMSESK EDQWMGVTVQ 120
SQGPGGKVVT CAHRYEKRQH VNTKQESRDI FGRCYVLSQN LRIEDDMDGG DWSFCDGRLR 180
GHEKFGSCQQ GVAATFTKDF HYIVFGAPGT YNWKGIVRVE QKNNTFFDMN IFEDGPYEVG 240
GETDHDESLV PVPANSYLGF SLDSGKGIVS KDDITFVSGA PRANHSGAVV LLKRDMKSAH 300
LLLEYIFDGE GLASSFGYDV AVVDLNADGW QDIVIGAPQY FDRDGEVGGA VYVYINQQGR 360
WSNVKPVRLN GTKDSMFGIA VKNIGDINQD GYPDIAVGAP YDDLGKVFIY HGSPTGIITK 420
PTQVLEGTTP FFGYSIAGNM DLDRNSYPDV AVGSLSDSVT IFRSRPVINI LKTITVTPSR 480
IDLRQKSMCG SPSGICLKVK ACFEYTAKPS GYNPPISILG ILEAEKERRK SGLSSRVQFR 540
NQGSEPKYTQ ELTLNRQKQR ACMEETLWLQ ENIRDKLRPI PITASVEIQE PSSRRRVNSL 600
PEVLPILNSN EAKTVQTDVH FLKEGCGDDN VCNSNLKLEY KFGTREGNQD KFSYLPIQKG 660
IPELVLKDQK DIALEITVTN GPSDPRNPRK DGDDAHEAKL IATFPDTLTY SAYRELRAFP 720
EKQLSCVANQ NGSQADCELG NPFKRNSSVT FYLILSTTEV TFDTTDLDIN LKLETTSNQD 780
NLAPITAKAK VVIELLLSVS GVAKPSQVYF GGTVVGEQAM KSEDEVGSLI EYEFRVINLG 840
KPLKNLGTAT LNIQWPKEIS NGKWLLYLMK VESKGLEQVV CEPHNEINFL KLKESHNSRK 900
KRELPEKQID DSRKFSLFSE RKYQTLNCSV NVRCVNIRCP LRGLDSKASL VLRSRLWNST 960
FLEEYSKLNY LDILVRASID VTAAAQNIKL PHAGTQVRVT VFPSKTVAQY SGIAWWIILL 1020
AVLAGILMLA LLVFLLWKCG FFKRNKKDHY DATYHKAEIH TQPSDKERLT SDA 1073 
Gene Ontology
 GO:0034676; C:alpha6-beta4 integrin complex; IDA:RGD.
 GO:0005913; C:cell-cell adherens junction; IDA:RGD.
 GO:0030175; C:filopodium; IDA:RGD.
 GO:0032403; F:protein complex binding; IDA:RGD.
 GO:0016337; P:cell-cell adhesion; IMP:RGD.
 GO:0071407; P:cellular response to organic cyclic compound; IEP:RGD.
 GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
 GO:0010811; P:positive regulation of cell-substrate adhesion; IMP:RGD. 
Interpro
 IPR013519; Int_alpha_beta-p.
 IPR000413; Integrin_alpha.
 IPR013649; Integrin_alpha-2.
 IPR018184; Integrin_alpha_C_CS. 
Pfam
 PF00357; Integrin_alpha
 PF08441; Integrin_alpha2 
SMART
 SM00191; Int_alpha 
PROSITE
 PS51470; FG_GAP
 PS00242; INTEGRIN_ALPHA 
PRINTS
 PR01185; INTEGRINA.