CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024406
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transmembrane protein 131-like 
Protein Synonyms/Alias
  
Gene Name
 KIAA0922 
Gene Synonyms/Alias
 TMEM131L 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
353KIASFTCKAATSCDSubiquitination[1]
367SGIIEDVKKTTHTPTubiquitination[1]
368GIIEDVKKTTHTPTLubiquitination[1]
729FGARELLKVGGRLPGubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
  
Sequence Annotation
 MOD_RES 1122 1122 Phosphoserine.
 MOD_RES 1328 1328 Phosphothreonine.
 MOD_RES 1331 1331 Phosphoserine.
 CARBOHYD 343 343 N-linked (GlcNAc...) (Potential).
 CARBOHYD 439 439 N-linked (GlcNAc...) (Potential).
 CARBOHYD 522 522 N-linked (GlcNAc...) (Potential).
 CARBOHYD 593 593 N-linked (GlcNAc...) (Potential).
 CARBOHYD 709 709 N-linked (GlcNAc...) (Potential).
 CARBOHYD 846 846 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Complete proteome; Glycoprotein; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1609 AA 
Protein Sequence
MAGLRRPQPG CYCRTAAAVN LLLGVFQVLL PCCRPGGAQG QAIEPLPNVV ELWQAEEGEL 60
LLPTQGDSEE GLEEPSQEQS FSDKLFSGKG LHFQPSVLDF GIQFLGHPVA KILHAYNPSR 120
DSEVVVNSVF AAAGHFHVPP VPCRVIPAMG KTSFRIIFLP TEEGSIESSL FINTSSYGVL 180
SYHVSGIGTR RISTEGSAKQ LPNAYFLLPK VQSIQLSQMQ AETTNTSLLQ VQLECSLHNK 240
VCQQLKGCYL ESDDVLRLQM SIMVTMENFS KEFEENTQHL LDHLSIVYVA TDESETSDDS 300
AVNMYILHSG NSLIWIQDIR HFSQRDALSL QFEPVLLPTS TTNFTKIASF TCKAATSCDS 360
GIIEDVKKTT HTPTLKACLF SSVAQGYFRM DSSATQFHIE THENTSGLWS IWYRNHFDRS 420
VVLNDVFLSK ETKHMLKILN FTGPLFLPPG CWNIFSLKLA VKDIAINLFT NVFLTTNIGA 480
IFAIPLQIYS APTKEGSLGF EVIAHCGMHY FMGKSKAGNP NWNGSLSLDQ STWNVDSELA 540
NKLYERWKKY KNGDVCKRNV LGTTRFAHLK KSKESESFVF FLPRLIAEPG LMLNFSATAL 600
RSRMIKYFVV QNPSSWPVSL QLLPLSLYPK PEALVHLLHR WFGTDMQMIN FTTGEFQLTE 660
ACPYLGTHSE ESRFGILHLH LQPLEMKRVG VVFTPADYGK VTSLILIRNN LTVIDMIGVE 720
GFGARELLKV GGRLPGAGGS LRFKVPESTL MDCRRQLKDS KQILSITKNF KVENIGPLPI 780
TVSSLKINGY NCQGYGFEVL DCHQFSLDPN TSRDISIVFT PDFTSSWVIR DLSLVTAADL 840
EFRFTLNVTL PHHLLPLCAD VVPGPSWEES FWRLTVFFVS LSLLGVILIA FQQAQYILME 900
FMKTRQRQNA SSSSQQNNGP MDVISPHSYK SNCKNFLDTY GPSDKGRGKN CLPVNTPQSR 960
IQNAAKRSPA TYGHSQKKHK CSVYYSKHKT STAAASSTST TTEEKQTSPL GSSLPAAKED 1020
ICTDAMRENW ISLRYASGIN VNLQKNLTLP KNLLNKEENT LKNTIVFSNP SSECSMKEGI 1080
QTCMFPKETD IKTSENTAEF KERELCPLKT SKKLPENHLP RNSPQYHQPD LPEISRKNNG 1140
NNQQVPVKNE VDHCENLKKV DTKPSSEKKI HKTSREDMFS EKQDIPFVEQ EDPYRKKKLQ 1200
EKREGNLQNL NWSKSRTCRK NKKRGVAPVS RPPEQSDLKL VCSDFERSEL SSDINVRSWC 1260
IQESTREVCK ADAEIASSLP AAQREAEGYY QKPEKKCVDK FCSDSSSDCG SSSGSVRASR 1320
GSWGSWSSTS SSDGDKKPMV DAQHFLPAGD SVSQNDFPSE APISLNLSHN ICNPMTVNSL 1380
PQYAEPSCPS LPAGPTGVEE DKGLYSPGDL WPTPPVCVTS SLNCTLENGV PCVIQESAPV 1440
HNSFIDWSAT CEGQFSSAYC PLELNDYNAF PEENMNYANG FPCPADVQTD FIDHNSQSTW 1500
NTPPNMPAAW GHASFISSPP YLTSTRSLSP MSGLFGSIWA PQSDVYENCC PINPTTEHST 1560
HMENQAVVCK EYYPGFNPFR AYMNLDIWTT TANRNANFPL SRDSSYCGNV 1610 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR022113; DUF3651_TMEM131. 
Pfam
 PF12371; DUF3651 
SMART
  
PROSITE
  
PRINTS