UniProt Accession

 SUFC_ECOLI; P77499 

Genbank Protein ID

 U00096; AP009048 

Genbank Nucleotide ID

 AAC74752.1; BAA15455.1 

Protein Name

 Probable ATP-dependent transporter SufC 

Protein Synonyms/Alias

  

Gene Name

 sufC 

Gene Synonyms/Alias

 ynhD; b1682; JW1672 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
14	LHVSVEDKAILRGLS	acetylation	[1]
132	EEKIALLKMPEDLLT	acetylation	[1]
151	VGFSGGEKKRNDILQ	acetylation	[1]
212	QRILDYIKPDYVHVL	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation. 

Sequence Annotation

 DOMAIN 2 246 ABC transporter.
 NP_BIND 34 41 ATP (Potential).  

Keyword

 3D-structure; ATP-binding; Complete proteome; Cytoplasm; Nucleotide-binding; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 248 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC.
 GO:0016226; P:iron-sulfur cluster assembly; IMP:EcoCyc.
 GO:0006810; P:transport; IEA:UniProtKB-KW. 

Interpro

 IPR003593; AAA+_ATPase.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR010230; FeS-cluster_ATPase_SufC.
 IPR027417; P-loop_NTPase. 

Pfam

 PF00005; ABC_tran 

SMART

 SM00382; AAA 

PROSITE

 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 

PRINTS