CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038585
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 WD repeat and SOCS box-containing protein 2 
Protein Synonyms/Alias
  
Gene Name
 Wsb2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
372PRVLSSLKHLCRKALubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 406 AA 
Protein Sequence
MISPSPEEPL LLAELKPGRP HQFDWKSSCE TWSVAFSPDG SWFAWSQGHC VVKLVPWPLE 60
EQFIPKGFEA KSRSSKNDPK GRGSLKEKTL DCGQIVWGLA FSPWPSPPSR KLWARHHPQA 120
PDVSCLILAT GLNDGQIKIW EVQTGLLLLN LSGHQDVVRD LSFTPSGSLI LVSASRDKTL 180
RIWDLNKHGK QIQVLSGHLQ WVYCCSISPD CSMLCSAAGE KSVFLWSMRS YTLIRKLEGH 240
QSSVVSCDFS PDSALLVTAS YDTSVIMWDP YTGERLRSLH HTQLEPTMDD SDVHMSSLRS 300
VCFSPEGLYL ATVADDRLLR IWALELKAPV AFAPMTNGLC CTFFPHGGII ATGTRDGHVQ 360
FWTAPRVLSS LKHLCRKALR SFLTTYQVLA LPIPKKMKEF LTYRTF 406 
Gene Ontology
 GO:0035556; P:intracellular signal transduction; IEA:InterPro.
 GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway. 
Interpro
 IPR020472; G-protein_beta_WD-40_rep.
 IPR001496; SOCS_C.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF07525; SOCS_box
 PF00400; WD40 
SMART
 SM00253; SOCS
 SM00969; SOCS_box
 SM00320; WD40 
PROSITE
 PS50225; SOCS
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00320; GPROTEINBRPT.