UniProt Accession

 RRFM_MOUSE; Q9D6S7; B1B055 

Genbank Protein ID

 AK010018; AK032371; BX293557; BC019787 

Genbank Nucleotide ID

 BAB26646.1; BAC27839.1; CAM20861.1; AAH19787.1 

Protein Name

 Ribosome-recycling factor, mitochondrial 

Protein Synonyms/Alias

 RRF; Ribosome-releasing factor, mitochondrial 

Gene Name

 Mrrf 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
100	KSVVEALKDNFNKTL	acetylation	[1]
195	EHREMLVKLAKQNTN	acetylation	[1]
223	MNKLKKSKDKTSEDT	acetylation	[1, 2]
225	KLKKSKDKTSEDTIR	acetylation	[1]

Reference

 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753] 

Functional Description

 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity). 

Sequence Annotation

  

Keyword

 3D-structure; Complete proteome; Mitochondrion; Protein biosynthesis; Reference proteome; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 262 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0006412; P:translation; IEA:UniProtKB-KW. 

Interpro

 IPR024946; Arg_repress_C-like.
 IPR002661; Ribosome_recyc_fac.
 IPR023584; Ribosome_recyc_fac_dom. 

Pfam

 PF01765; RRF 

SMART

  

PROSITE

  

PRINTS