CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002896
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Amino-acid acetyltransferase 
Protein Synonyms/Alias
 N-acetylglutamate synthase; AGS; NAGS 
Gene Name
 argA 
Gene Synonyms/Alias
 b2818; JW2786 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
6**MVKERKTELVEGFacetylation[1]
92NIRVTDAKTLELVKQacetylation[1]
240RVEAQEEKGDYNSGTacetylation[1]
425IDLLPESKKQLYNYQacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
  
Sequence Annotation
 DOMAIN 296 443 N-acetyltransferase.  
Keyword
 Acyltransferase; Amino-acid biosynthesis; Arginine biosynthesis; Complete proteome; Cytoplasm; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 443 AA 
Protein Sequence
MVKERKTELV EGFRHSVPYI NTHRGKTFVI MLGGEAIEHE NFSSIVNDIG LLHSLGIRLV 60
VVYGARPQID ANLAAHHHEP LYHKNIRVTD AKTLELVKQA AGTLQLDITA RLSMSLNNTP 120
LQGAHINVVS GNFIIAQPLG VDDGVDYCHS GRIRRIDEDA IHRQLDSGAI VLMGPVAVSV 180
TGESFNLTSE EIATQLAIKL KAEKMIGFCS SQGVTNDDGD IVSELFPNEA QARVEAQEEK 240
GDYNSGTVRF LRGAVKACRS GVRRCHLISY QEDGALLQEL FSRDGIGTQI VMESAEQIRR 300
ATINDIGGIL ELIRPLEQQG ILVRRSREQL EMEIDKFTII QRDNTTIACA ALYPFPEEKI 360
GEMACVAVHP DYRSSSRGEV LLERIAAQAK QSGLSKLFVL TTRSIHWFQE RGFTPVDIDL 420
LPESKKQLYN YQRKSKVLMA DLG 443 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004042; F:acetyl-CoA:L-glutamate N-acetyltransferase activity; IEA:HAMAP.
 GO:0004358; F:glutamate N-acetyltransferase activity; IDA:EcoCyc.
 GO:0006526; P:arginine biosynthetic process; IDA:EcoCyc. 
Interpro
 IPR016181; Acyl_CoA_acyltransferase.
 IPR001048; Asp/Glu/Uridylate_kinase.
 IPR000182; GNAT_dom.
 IPR010167; NH2A_AcTrfase_ArgA. 
Pfam
 PF00696; AA_kinase
 PF00583; Acetyltransf_1 
SMART
  
PROSITE
 PS51186; GNAT 
PRINTS