UniProt Accession

 E7EQJ3_HUMAN; E7EQJ3 

Genbank Protein ID

 AC011372; AC011388 

Genbank Nucleotide ID

  

Protein Name

 HLA class II histocompatibility antigen gamma chain 

Protein Synonyms/Alias

  

Gene Name

 CD74 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
43	RPGAPESKCSRGALY	ubiquitination	[1]
80	QQQGRLDKLTVTSQN	ubiquitination	[1]
96	QLENLRMKLPKPHAE	methylation	[2]
99	NLRMKLPKPHAECHQ	methylation	[2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 122 AA 

Protein Sequence

Gene Ontology

 GO:0016020; C:membrane; IEA:InterPro.
 GO:0019882; P:antigen processing and presentation; IEA:InterPro.
 GO:0006955; P:immune response; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; IEA:InterPro. 

Interpro

 IPR015386; MHC_II-assoc_invar/CLIP_MHC-bd.
 IPR022339; MHC_II-assoc_invar_chain. 

Pfam

 PF09307; MHC2-interact 

SMART

  

PROSITE

  

PRINTS

 PR01990; CD74ANTIGEN.