UniProt Accession

 AT5G1_HUMAN; P05496 

Genbank Protein ID

 X69907; D13118; AL080089; BT007230; BC004963; M16453 

Genbank Nucleotide ID

 CAA49532.1; BAA02420.1; CAB45704.1; AAP35894.1; AAH04963.1; AAA51806.1 

Protein Name

 ATP synthase lipid-binding protein, mitochondrial 

Protein Synonyms/Alias

 ATP synthase proteolipid P1; ATPase protein 9; ATPase subunit c 

Gene Name

 ATP5G1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
104	YARNPSLKQQLFSYA	methylation	[1, 2]

Reference

 [1] Mitochondrial ATP synthase subunit c stored in hereditary ceroid-lipofuscinosis contains trimethyl-lysine.
 Katz ML, Gao CL, Tompkins JA, Bronson RT, Chin DT.
 Biochem J. 1995 Sep 15;310 ( Pt 3):887-92. [PMID: 7575423]
 [2] Lysine 43 is trimethylated in subunit C from bovine mitochondrial ATP synthase and in storage bodies associated with batten disease.
 Chen R, Fearnley IM, Palmer DN, Walker JE.
 J Biol Chem. 2004 May 21;279(21):21883-7. [PMID: 15010464] 

Functional Description

 Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element. 

Sequence Annotation

  

Keyword

 CF(0); Complete proteome; Hydrogen ion transport; Ion transport; Lipid-binding; Membrane; Mitochondrion; Reference proteome; Transit peptide; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 136 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005753; C:mitochondrial proton-transporting ATP synthase complex; ISS:UniProtKB.
 GO:0045263; C:proton-transporting ATP synthase complex, coupling factor F(o); IEA:UniProtKB-KW.
 GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
 GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
 GO:0005215; F:transporter activity; NAS:ProtInc.
 GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
 GO:0042776; P:mitochondrial ATP synthesis coupled proton transport; TAS:Reactome.
 GO:0022904; P:respiratory electron transport chain; TAS:Reactome. 

Interpro

 IPR000454; ATPase_F0-cplx_csu.
 IPR020537; ATPase_F0-cplx_csu_DDCD_BS.
 IPR002379; ATPase_proteolipid_c_like_dom. 

Pfam

 PF00137; ATP-synt_C 

SMART

  

PROSITE

 PS00605; ATPASE_C 

PRINTS

 PR00124; ATPASEC.