CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017589
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein FAM63B 
Protein Synonyms/Alias
  
Gene Name
 FAM63B 
Gene Synonyms/Alias
 KIAA1164 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
234AQVLAASKERFPGQSubiquitination[1, 2, 3]
309YMLDAKPKEISEIQRubiquitination[1, 3]
393SYNQLVEKIISCKQSubiquitination[4]
454NHFSTMTKYKGQLYLubiquitination[2]
548SDLELAKKLQEEEDRubiquitination[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
 MOD_RES 94 94 Phosphoserine.
 MOD_RES 233 233 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; Complete proteome; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 621 AA 
Protein Sequence
MESSPESLQP LEHGVAAGPA SGTGSSQEGL QETRLAAGDG PGVWAAETSG GNGLGAAAAR 60
RSLPDSASPA GSPEVPGPCS SSAGLDLKDS GLESPAAAEA PLRGQYKVTA SPETAVAGVG 120
HELGTAGDAG ARPDLAGTCQ AELTAAGSEE PSSAGGLSSS CSDPSPPGES PSLDSLESFS 180
NLHSFPSSCE FNSEEGAENR VPEEEEGAAV LPGAVPLCKE EEGEETAQVL AASKERFPGQ 240
SVYHIKWIQW KEENTPIITQ NENGPCPLLA ILNVLLLAWK VKLPPMMEII TAEQLMEYLG 300
DYMLDAKPKE ISEIQRLNYE QNMSDAMAIL HKLQTGLDVN VRFTGVRVFE YTPECIVFDL 360
LDIPLYHGWL VDPQIDDIVK AVGNCSYNQL VEKIISCKQS DNSELVSEGF VAEQFLNNTA 420
TQLTYHGLCE LTSTVQEGEL CVFFRNNHFS TMTKYKGQLY LLVTDQGFLT EEKVVWESLH 480
NVDGDGNFCD SEFHLRPPSD PETVYKGQQD QIDQDYLMAL SLQQEQQSQE INWEQIPEGI 540
SDLELAKKLQ EEEDRRASQY YQEQEQAAAA AAAASTQAQQ GQPAQASPSS GRQSGNSERK 600
RKEPREKDKE KEKEKNSCVI L 621 
Gene Ontology
  
Interpro
 IPR007518; DUF544. 
Pfam
 PF04424; DUF544 
SMART
  
PROSITE
  
PRINTS