UniProt Accession

 RL12B_YEAST; P0CX54; D3DLJ6; P05741; P17079 

Genbank Protein ID

 X51520; U33007; BK006938 

Genbank Nucleotide ID

 CAA35892.1; AAB64852.1; DAA12258.1 

Protein Name

 60S ribosomal protein L12-B 

Protein Synonyms/Alias

 L15; YL23 

Gene Name

 RPL12B 

Gene Synonyms/Alias

 RPL15A; YDR418W; D9461.7 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
11	KFDPNEVKYLYLRAV	methylation	[1]
31	ASAALAPKIGPLGLS	ubiquitination	[2]
48	KVGEDIAKATKEFKG	ubiquitination	[2]
51	EDIAKATKEFKGIKV	ubiquitination	[2]
130	RTLASVTKEILGTAQ	ubiquitination	[2]
146	VGCRVDFKNPHDIIE	ubiquitination	[2]

Reference

 [1] Update on activities at the Universal Protein Resource (UniProt) in 2013.
 e="String">UniProt Consortium.
 Nucleic Acids Res. 2013 Jan;41(Database issue):D43-7. [PMID: 23161681]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 

Functional Description

 This protein binds directly to 26S ribosomal RNA. 

Sequence Annotation

 MOD_RES 2 2 N,N-dimethylproline; by NTM1.
 MOD_RES 4 4 N6,N6,N6-trimethyllysine; by RKM2.
 MOD_RES 11 11 N6,N6,N6-trimethyllysine; by RKM2.
 MOD_RES 25 25 Phosphoserine.
 MOD_RES 38 38 Phosphoserine.
 MOD_RES 67 67 N5-methylarginine; by RMT2.  

Keyword

 Complete proteome; Cytoplasm; Direct protein sequencing; Methylation; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 165 AA 

Protein Sequence

Gene Ontology

 GO:0022625; C:cytosolic large ribosomal subunit; TAS:SGD.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
 GO:0003735; F:structural constituent of ribosome; TAS:SGD.
 GO:0002181; P:cytoplasmic translation; TAS:SGD.
 GO:0000027; P:ribosomal large subunit assembly; IMP:SGD. 

Interpro

 IPR000911; Ribosomal_L11.
 IPR020783; Ribosomal_L11_C.
 IPR020785; Ribosomal_L11_CS.
 IPR020784; Ribosomal_L11_N. 

Pfam

 PF00298; Ribosomal_L11
 PF03946; Ribosomal_L11_N 

SMART

 SM00649; RL11 

PROSITE

 PS00359; RIBOSOMAL_L11 

PRINTS