UniProt Accession

 NSA2_YEAST; P40078; D3DM32 

Genbank Protein ID

 U18916; AY693192; BK006939 

Genbank Nucleotide ID

 AAC03224.1; AAT93211.1; DAA07786.1 

Protein Name

 Ribosome biogenesis protein NSA2 

Protein Synonyms/Alias

 NOP7-associated protein 2 

Gene Name

 NSA2 

Gene Synonyms/Alias

 YER126C; SYGP-ORF47 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
117	KRLEKADKFSVPLPK	acetylation	[1]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles. Under normal, rapid growth conditions, high levels of NSA2 would allow the progression of pre-60S particles through the ITS2 processing. 

Sequence Annotation

  

Keyword

 Complete proteome; Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 261 AA 

Protein Sequence

Gene Ontology

 GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0030687; C:preribosome, large subunit precursor; IDA:SGD.
 GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
 GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD. 

Interpro

 IPR022309; Ribosomal_S8e/biogenesis_NSA2. 

Pfam

 PF01201; Ribosomal_S8e 

SMART

  

PROSITE

  

PRINTS