UniProt Accession

 BAER_ECOLI; P69228; P30846 

Genbank Protein ID

 D14054; U00096; AP009048 

Genbank Nucleotide ID

 BAA03141.1; AAC75140.1; BAA15935.1 

Protein Name

 Transcriptional regulatory protein BaeR 

Protein Synonyms/Alias

  

Gene Name

 baeR 

Gene Synonyms/Alias

 b2079; JW2064 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
157	FQASWRGKMLDLTPA	acetylation	[1]
178	TLSHEPGKVFSREQL	acetylation	[1]
206	RTIDSHIKNLRRKLE	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Member of the two-component regulatory system BaeS/BaeR. Activates the mdtABCD and probably the casABCDE-ygbT-ygbF operons. 

Sequence Annotation

 DOMAIN 12 125 Response regulatory.
 MOD_RES 61 61 4-aspartylphosphate (By similarity).  

Keyword

 Complete proteome; Cytoplasm; DNA-binding; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Two-component regulatory system. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 240 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0000986; F:bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding; IDA:EcoCyc.
 GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
 GO:0035556; P:intracellular signal transduction; IEA:GOC.
 GO:2000144; P:positive regulation of DNA-dependent transcription, initiation; IDA:EcoCyc.
 GO:2001023; P:regulation of response to drug; IMP:EcoCyc.
 GO:0006351; P:transcription, DNA-dependent; IDA:EcoCyc. 

Interpro

 IPR011006; CheY-like_superfamily.
 IPR001867; Sig_transdc_resp-reg_C.
 IPR016032; Sig_transdc_resp-reg_C-effctor.
 IPR001789; Sig_transdc_resp-reg_receiver.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF00072; Response_reg
 PF00486; Trans_reg_C 

SMART

 SM00448; REC
 SM00862; Trans_reg_C 

PROSITE

 PS50110; RESPONSE_REGULATORY 

PRINTS