CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005420
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein PBN1 
Protein Synonyms/Alias
 Protease B non-derepressible protein 1 
Gene Name
 PBN1 
Gene Synonyms/Alias
 YCL052C; YCL52C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
285PEYSLRDKAWGSESIubiquitination[1]
Reference
 [1] Identification, analysis, and prediction of protein ubiquitination sites.
 Radivojac P, Vacic V, Haynes C, Cocklin RR, Mohan A, Heyen JW, Goebl MG, Iakoucheva LM.
 Proteins. 2010 Feb 1;78(2):365-80. [PMID: 19722269
Functional Description
 Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Aids the autocatalytic processing of PRB1. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14. 
Sequence Annotation
 CARBOHYD 24 24 N-linked (GlcNAc...) (Potential).
 CARBOHYD 85 85 N-linked (GlcNAc...) (Potential).
 CARBOHYD 120 120 N-linked (GlcNAc...) (Potential).
 CARBOHYD 212 212 N-linked (GlcNAc...) (Potential).
 CARBOHYD 365 365 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Endoplasmic reticulum; Glycoprotein; GPI-anchor biosynthesis; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 416 AA 
Protein Sequence
MVTRHRVTVL YNAPEDIGNH MRQNDTHLTV RGGSGVVLQQ RWLLERTGSL DKSFTRITWR 60
PRADLARSLS VIENELSAGF SVYSNSSDVP ERFITNPVYN SFHSEKFDIE QYLPPEVDLN 120
LSWNPEDFTY DISVEPTQIQ IVEYRLLKQG EEFTIARVKD EKLEVGVFFV DASDESDVDI 180
GGIRCNWRMD DGKMERCQKT SLLYKQGHIA YNHSTTTTSL YLNEPIGLHP KIMIDLTDFE 240
ERPKCMYLMH LQLPLELFID KFQSSPLLLF GEDDLELPEY SLRDKAWGSE SIFELKAGTM 300
NEVTLHTRYI EPSNNKGDKL EVSFDPEVIL ACDTGDNKVS RNPFYKKGLG YESLFTDDTT 360
FRHLNSTTLL VPIPRPDTKD YSKIKNGTLL CLLISIIYIF SKVFGNNKKK RSVKRE 416 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IDA:SGD.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0030433; P:ER-associated protein catabolic process; IMP:SGD.
 GO:0006506; P:GPI anchor biosynthetic process; IMP:SGD.
 GO:0016485; P:protein processing; IMP:SGD. 
Interpro
 IPR013233; PIG-X/PBN1. 
Pfam
 PF08320; PIG-X 
SMART
 SM00780; PIG-X 
PROSITE
  
PRINTS