UniProt Accession

 TBG1_MOUSE; P83887; Q9Z310 

Genbank Protein ID

 BC006581 

Genbank Nucleotide ID

 AAH06581.1 

Protein Name

 Tubulin gamma-1 chain 

Protein Synonyms/Alias

 Gamma-1-tubulin; Gamma-tubulin complex component 1; GCP-1 

Gene Name

 Tubg1 

Gene Synonyms/Alias

 Tubg 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
410	AFMEQFRKEDIFKDN	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity). 

Sequence Annotation

 NP_BIND 142 148 GTP (Potential).
 MOD_RES 131 131 Phosphoserine; by BRSK1.  

Keyword

 Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; GTP-binding; Microtubule; Nucleotide-binding; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 451 AA 

Protein Sequence

Gene Ontology

 GO:0045177; C:apical part of cell; IDA:MGI.
 GO:0031252; C:cell leading edge; IDA:MGI.
 GO:0005814; C:centriole; IDA:MGI.
 GO:0005929; C:cilium; IDA:MGI.
 GO:0000794; C:condensed nuclear chromosome; IDA:UniProtKB.
 GO:0005881; C:cytoplasmic microtubule; IDA:MGI.
 GO:0000930; C:gamma-tubulin complex; IEA:Compara.
 GO:0000242; C:pericentriolar material; IDA:MGI.
 GO:0005827; C:polar microtubule; ISS:UniProtKB.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0005200; F:structural constituent of cytoskeleton; TAS:UniProtKB.
 GO:0000212; P:meiotic spindle organization; IEP:UniProtKB.
 GO:0007020; P:microtubule nucleation; TAS:UniProtKB.
 GO:0007052; P:mitotic spindle organization; TAS:UniProtKB.
 GO:0051258; P:protein polymerization; IEA:InterPro.
 GO:0007088; P:regulation of mitosis; TAS:UniProtKB. 

Interpro

 IPR002454; Gamma_tubulin.
 IPR008280; Tub_FtsZ_C.
 IPR000217; Tubulin.
 IPR018316; Tubulin/FtsZ_2-layer-sand-dom.
 IPR023123; Tubulin_C.
 IPR017975; Tubulin_CS.
 IPR003008; Tubulin_FtsZ_GTPase. 

Pfam

 PF00091; Tubulin
 PF03953; Tubulin_C 

SMART

 SM00864; Tubulin
 SM00865; Tubulin_C 

PROSITE

 PS00227; TUBULIN 

PRINTS

 PR01164; GAMMATUBULIN.
 PR01161; TUBULIN.