UniProt Accession

 VAPB_MOUSE; Q9QY76 

Genbank Protein ID

 AF115504 

Genbank Nucleotide ID

 AAF23077.1 

Protein Name

 Vesicle-associated membrane protein-associated protein B 

Protein Synonyms/Alias

 VAMP-B; VAMP-associated protein B; VAP-B; VAMP-associated protein 33b 

Gene Name

 Vapb 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
118	PEDLMDSKLRCVFEL	acetylation	[1]
131	ELPAENAKPHDVEIN	acetylation	[1]
191	REESRQLKEEDGLRV	acetylation	[1]

Reference

 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 

Functional Description

 Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity (By similarity). Involved in cellular calcium homeostasis regulation (By similarity). 

Sequence Annotation

 DOMAIN 7 124 MSP.
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 156 156 Phosphoserine (By similarity).  

Keyword

 Acetylation; Coiled coil; Complete proteome; Endoplasmic reticulum; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Unfolded protein response. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 243 AA 

Protein Sequence

Gene Ontology

 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0016020; C:membrane; IDA:BHF-UCL.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; ISS:UniProtKB.
 GO:0006874; P:cellular calcium ion homeostasis; ISS:UniProtKB. 

Interpro

 IPR000535; Major_sperm.
 IPR008962; PapD-like.
 IPR016763; Vesicle-associated_membrane. 

Pfam

 PF00635; Motile_Sperm 

SMART

  

PROSITE

 PS50202; MSP 

PRINTS