CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024199
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Fer-1-like protein 5 
Protein Synonyms/Alias
  
Gene Name
 FER1L5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
1284AWGLRNMKKASSPQLmethylation[1]
Reference
 [1] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510
Functional Description
 Plays a role in myoblast fusion; probable mediator of endocytic recycling for membrane trafficking events during myotube formation (By similarity). 
Sequence Annotation
 DOMAIN 1 83 C2 1.
 DOMAIN 154 292 C2 2.
 DOMAIN 295 391 C2 3.
 DOMAIN 1090 1195 C2 4.
 DOMAIN 1500 1598 C2 5.
 DOMAIN 1744 1872 C2 6.  
Keyword
 Alternative splicing; Cell membrane; Complete proteome; Membrane; Polymorphism; Reference proteome; Repeat; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2093 AA 
Protein Sequence
MLRLVVQSAK IDPPLAPLPR PCMSIDFRDI KKRTRVVEGN DPVWNETLIW HLWNRPLEND 60
SFLQVTLQDM GSQKKERFIG LATVLLKPLL KQPSEVLFVK DLTLLNHSMK PTDCTVTLQV 120
AHMSNQDIEK TGAEDHLGIT AREAASQKLM VPGSTAHRAL SSKPQHFQVR VKVFEARQLM 180
GNNIKPVVKV SIAGQQHQTR IKMGNNPFFN EIFFQNFHEV PAKFFDETIL IQTDIGFIYH 240
SPGHTLLRKW LGLCQPNNPG SGVTGYLKVT IYALGVGDQA LIDQKLLYGT DDTDIQIFKS 300
AVVPINMAYL QLFIYCAEDL HLKKHQSVNP QLEVELIGEK LRTHMQTQTD NPIWNQILTF 360
RIQLPCLSSY IKFRVLDCRK KDCPDEIGTA SLSLNQISST GEEIEGKQSL EPTSYTPRVY 420
SGFLPCFGPS FLTLHGGKKA PFRIQEEGAC IPDSVRDGLA YRGRVFLELI TQIKSYQDST 480
IKDLSHEVTR IEKHQNRQKY GLCVIFLSCT MMPNFKELIH FEVSIGHYGN KMDLNYKPLV 540
SSTPYSPVIY DGNIYHYVPW YNTKPVVAVT SNWEDVSFRM NCLNLLHFTR DRLKANLDTL 600
KSTRNPKDPA LLYQWEKLLR ELAEDCKRPL PCMTYQPKAT SLDRKRWQLR SLLLQELAQK 660
AKQAKPKDMV ATAEDWLYRL NTVLPEPQMG LPDVMIWLVA KEQRVAYAQV PAHSVLFSPA 720
GALHSGRLCG KIQTLFLQYP EGEGQKDVLP AHLRVCMWLG NVTDSKDLQL LRQGDTAVYA 780
EMYENQAKYK DQWGQQGLYH CPNFSDVMGN KTLPMTDFQP PLGWHWQDSW TVEPQRRLLL 840
DIDINKSQVL EEVYENQGRD TRGAWGPAAI PNTDVNGQPM EARENVKCPQ GWHFKKDWVV 900
ELNHAVDSWE YGVGIPPSGL PQVWSPVEKT YHSCRRRRWA RVRFRNHGEL SHEQETLSFL 960
QLGLAKGEEE GWEYDTFGSK FHLNPQPQSR FRRRCWRRRL APNKDKGIAP IFLLEGSLAC 1020
EGGSVREEGD WAWARGNRSS TQEPQGRLSW VQAMDLKYHA GKEEDSKTWP WGLDRQFRDP 1080
QRQDTRPPNL PFIYCTFNKP HYYQLFCYIY QARNLVSNQI LTFQGPFIRV VFLNHSQCTQ 1140
TLRSSAGPTW AQTLIFQHLL LYENPQDTKE SPPLVVLELW QRDFWGKESL WGRSVWPPMV 1200
WLDLQDRILP PMRWHPLVKE LGKEEGEILA SCELILQTEK LGEKQLPILS VPWKNGAYTL 1260
PKSIQPTIKR MAIEILAWGL RNMKKASSPQ LLVEFGEESL RTEPIRDFQT NPNFPESESV 1320
LVLTVLMPTE EAYALPLVVK VVDNWAFGQQ TVTGQANIDF LQPYFCDPWA QDYMHPKLPT 1380
LSEKKHQDFL GYLYRKFWFK SSKAEDEYEH EVDWWSKLFW ATDEHKSLKY KYKDYHTLKV 1440
YECELEAVPA FQGLQDFCQT FKLYQEQPKL DSPVVGEFKG LFRIYPFPEN PEAPKPPLQF 1500
LVWPEREDFP QPCLVRVYMV RAINLQPQDY NGLCDPYVIL KLGKTELGNR DMYQPNTLDP 1560
IFGMMFELTC NIPLEKDLEI QLYDFDLFSP DDKIGTTVID LENRLLSGFG AHCGLSKSYC 1620
QSGPFRWRDQ MPPSYLLERY AKRKGLPPPL FSPEEDAVFY NGKKFKLQSF EPKTPTVHGL 1680
GPKKERLALY LLHTQGLVPE HVETRTLYSH SQPGIDQGKV QMWVDIFPKK LGPPGPQVNI 1740
NPRKPKRKAS EHSGHRYELR CIIWKTANVD LVDDNLSREK TSDIYIKGWL YGLEKDMQKT 1800
DIHYHSLTGE ADFNWRFIFT MDYLAAERTC VQSQKDYIWS LDATSMKFPA RLIIQVWDND 1860
IFSPDDFLGV LELDLSDMPL PARHAKQCSI RMMDADPKWP YFIQYKHFSL FKKKTVTGWW 1920
PCQVLDGGKW RLSGKVKMSL EILSEKEALI KPAGRGQSEP NQYPTLHPPL RTNTSFTWLR 1980
SPVQNFCYIF WKRYRFKLIA FMVISIIALM LFNFIYSAPH YLAMSWIKPQ LQLYPPIKIF 2040
NIINSLNTSN ASSSILPTQD PNLKPTIDHE WKLHPGPTNH LSDIFPELPA PGD 2093 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. 
Interpro
 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR018029; C2_membr_targeting.
 IPR012968; FerIin-domain.
 IPR012560; Ferlin_A-domain.
 IPR012561; Ferlin_B-domain.
 IPR006614; Peroxin/Ferlin. 
Pfam
 PF00168; C2
 PF08165; FerA
 PF08150; FerB
 PF08151; FerI 
SMART
 SM00239; C2
 SM00694; DysFC 
PROSITE
 PS50004; C2 
PRINTS