CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011709
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Copine-7 
Protein Synonyms/Alias
 Copine VII 
Gene Name
 Cpne7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
172DDKDLFSKSDPFLELubiquitination[1]
418NVAPIISKVARMAAAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity). 
Sequence Annotation
 DOMAIN 6 112 C2 1.
 DOMAIN 139 244 C2 2.
 DOMAIN 306 505 VWFA.  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 557 AA 
Protein Sequence
MSGDSERAVA PGVVPAPCAS KVELRLSCRH LLDRDPLTKS DPSVVLLQQA QGQWLQVDRT 60
EVVKSSLHPV FSKVFTVDYY FEGVQKLRFE VYDTHGPSGL TCQDDDFLGG MECTLGQIVA 120
QKKMTRPLLL RFGRNAGKST ITVIAEDISG NNGYVELSFQ ARKLDDKDLF SKSDPFLELY 180
RVNDDGSEQL VYRTEVVKNN LNPVWEPFKV SLNSLCSCEE TRPLKCLVWD YDSRGKHDFI 240
GDFTTTFAEM QKAFEEEQQA QWDCVNAKYK QKKRNYKNSG VVILADLKLH RVHSFLDYIM 300
GGCQIHCTVA IDFTASNGDP RNSCSLHHIN PYQPNEYLRA LVAVGEVCQD YDSDKRFSAL 360
GFGARIPPKY EVSHDFAINF NPEDDECEGI QGVVEAYQNC LPKVQLYGPT NVAPIISKVA 420
RMAAAEESTG EASQYYILLI LTDGVVTDMS DTREAIVRAS HLPMSVIIVG VGNADFTDMQ 480
ILDGDDGVLR SPRGEPALRD IVQFVPFREL KNASPAALAK CVLAEVPKQV VEYYSHKELP 540
PRSLGAQTGE AAASSAP 557 
Gene Ontology
 GO:0005886; C:plasma membrane; TAS:Reactome. 
Interpro
 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR018029; C2_membr_targeting.
 IPR010734; Copine.
 IPR002035; VWF_A. 
Pfam
 PF00168; C2
 PF07002; Copine 
SMART
 SM00239; C2
 SM00327; VWA 
PROSITE
 PS50004; C2
 PS50234; VWFA 
PRINTS