CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039028
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Cd2ap 
Protein Synonyms/Alias
  
Gene Name
 Cd2ap 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
55MFPDNFVKEIKRETEacetylation[1]
240SSETEEKKSEKPLILacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 637 AA 
Protein Sequence
LVDYIVEYDY DAVHDDELTI RVGEIIRNVK KLQEEGWLEG ELNGRRGMFP DNFVKEIKRE 60
TEPKDDNLPI KRERPGNVAS LVQRISTYGL PAGGIQPHPQ TKAMKKKTKK RQCKVLFEYS 120
PQNEDELELT VGDVIDVIEE VEEGWWSGTL NNKLGLFPSN FVKELESTDD GEMHDAQEES 180
EVSLTGPTSP MPSPGNGSEP APGSVTQPKK IRGVGFGDIF KEGSVKLRTR TSSSETEEKK 240
SEKPLILQSL GSRTQNVEVT KPDIDGKIKA KEYCKTVFPY TGTNEDELTF REGEIIHLIS 300
KETGEAGWWK GELNGKEGVF PDNFAVQISE LDKDFPKPKK PPPPAKGPAP KPDPLAGEKK 360
TFPLKAEDRD EKSLLEQKPS KPAAPQVPPK KPTPPTKANN LLRSPGTMYP KRPEKPVPPP 420
PPTAKINGEV STISSKIDTE PLSKPKLDPE QLPVRPKSVD LDALVARNSK ETDNVNFDDI 480
ASSENLLHLT ANRPKMPGRR LPGRFNGGHS PTQSPEKTLK LPKDDDSGNI KPSEFKKDAG 540
YSSKPSLSAP SSASKVNTAA FLSPLELKAK VEADDGKKSS LDELRAQIIE LLCIVDALKK 600
DHGKELEKLR RELEEEKAMR SNLEVEIAKL KKAVLLS 637 
Gene Ontology
 GO:0031252; C:cell leading edge; IDA:RGD.
 GO:0030139; C:endocytic vesicle; IDA:RGD.
 GO:0031941; C:filamentous actin; IEA:Compara.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0043234; C:protein complex; IDA:RGD.
 GO:0001726; C:ruffle; IEA:Compara.
 GO:0008013; F:beta-catenin binding; IDA:RGD.
 GO:0005172; F:vascular endothelial growth factor receptor binding; IDA:RGD.
 GO:0016477; P:cell migration; IMP:RGD.
 GO:0016337; P:cell-cell adhesion; IMP:RGD.
 GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:RGD.
 GO:0048259; P:regulation of receptor-mediated endocytosis; IDA:RGD.
 GO:0016050; P:vesicle organization; IDA:RGD. 
Interpro
 IPR000108; p67phox.
 IPR011511; SH3_2.
 IPR001452; SH3_domain. 
Pfam
 PF00018; SH3_1
 PF07653; SH3_2 
SMART
 SM00326; SH3 
PROSITE
 PS50002; SH3 
PRINTS
 PR00499; P67PHOX.
 PR00452; SH3DOMAIN.