CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028461
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Microtubule-associated protein tau 
Protein Synonyms/Alias
  
Gene Name
 Mapt 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
562PVPMPDLKNVRSKIGubiquitination[1]
589KVQIINKKLDLSNVQubiquitination[1]
598DLSNVQSKCGSKDNIubiquitination[1]
619GSVQIVYKPVDLSKVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 749 AA 
Protein Sequence
MADPRQEFDT MEDHAGDYTL LQDQEGDMDH GLKESPPQPP ADDGAEEPGS ETSDAKSTPT 60
AEDVTAPLVD ERAPDKQAAA QPHTEIPEGI TAEEAGIGDT PNQEDQAAGH VTQEPEKVEI 120
FSQSLLVEPG RREGQAPDLG TSDWTRQQVS SMSGAPLLPQ GLREATCQPS GTRPEDIEKS 180
HPASELLRRG PPQKEGWGQD RLGSEEEVDE DLTVDESSQD SPPSQASLTP GRAAPQAGSG 240
SVCGETASVP GLPTEGSVPL PADFFSKVSA ETQASQPEGP GTGPMEEGHE AAPEFTFHVE 300
IKASTPKEQD LEGATVVGVP GEEQKAQTQG PSVGKGTKEA SLQEPPGKQP AAGLPGRPVS 360
RVPQLKARVA SKDRTGNDEK KAKTSTPSCA KAPSHRPCLS PTRPTLGSSD PLIKPSSPAV 420
CPEPATSPKH VSSVTPRNGS PGTKQMKLKG ADGKTGAKIA TPRGAASPAQ KGTSNATRIP 480
AKTTPSPKTP PGSGEPPKSG ERSGYSSPGS PGTPGSRSRT PSLPTPPTRE PKKVAVVRTP 540
PKSPSASKSR LQTAPVPMPD LKNVRSKIGS TENLKHQPGG GKVQIINKKL DLSNVQSKCG 600
SKDNIKHVPG GGSVQIVYKP VDLSKVTSKC GSLGNIHHKP GGGQVEVKSE KLDFKDRVQS 660
KIGSLDNITH VPGGGNKKIE THKLTFRENA KAKTDHGAEI VYKSPVVSGD TSPRHLSNVS 720
STGSIDMVDS PQLATLADEV SASLAKQGL 749 
Gene Ontology
 GO:0030424; C:axon; IDA:MGI.
 GO:0035085; C:cilium axoneme; IDA:MGI.
 GO:0005874; C:microtubule; IDA:MGI.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0008017; F:microtubule binding; IDA:MGI.
 GO:0007628; P:adult walking behavior; IGI:MGI.
 GO:0008088; P:axon cargo transport; IGI:MGI.
 GO:0048675; P:axon extension; IMP:MGI.
 GO:0000226; P:microtubule cytoskeleton organization; IMP:MGI.
 GO:0047497; P:mitochondrion transport along microtubule; IMP:MGI.
 GO:0032387; P:negative regulation of intracellular transport; IMP:MGI.
 GO:0001764; P:neuron migration; IMP:MGI.
 GO:0045773; P:positive regulation of axon extension; IMP:MGI.
 GO:0060632; P:regulation of microtubule-based movement; IDA:MGI. 
Interpro
 IPR027324; MAP2/MAP4/Tau.
 IPR001084; Tau/MAP_tubulin-bd_rpt.
 IPR002955; Tau_protein. 
Pfam
 PF00418; Tubulin-binding 
SMART
  
PROSITE
 PS00229; TAU_MAP_1
 PS51491; TAU_MAP_2 
PRINTS
 PR01261; TAUPROTEIN.