CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013679
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein PRRC2B 
Protein Synonyms/Alias
 HLA-B-associated transcript 2-like 1; Proline-rich coiled-coil protein 2B 
Gene Name
 PRRC2B 
Gene Synonyms/Alias
 BAT2L; BAT2L1; KIAA0515 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
386VDYSEKLKFSDDEEEphosphoglycerylation[1]
398EEEEEVVKDGRPKWNphosphoglycerylation[1]
1510LPEASSKKAEKEAKLubiquitination[2]
Reference
 [1] Functional lysine modification by an intrinsically reactive primary glycolytic metabolite.
 Moellering RE, Cravatt BF.
 Science. 2013 Aug 2;341(6145):549-53. [PMID: 23908237]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
  
Sequence Annotation
 MOD_RES 166 166 Phosphoserine.
 MOD_RES 168 168 Phosphoserine.
 MOD_RES 226 226 Phosphoserine.
 MOD_RES 388 388 Phosphoserine.
 MOD_RES 416 416 Phosphoserine.
 MOD_RES 613 613 Phosphoserine (By similarity).
 MOD_RES 736 736 Phosphothreonine.
 MOD_RES 740 740 Phosphoserine.
 MOD_RES 745 745 Phosphoserine.
 MOD_RES 1132 1132 Phosphoserine.
 MOD_RES 1231 1231 Phosphoserine.
 MOD_RES 1470 1470 Phosphoserine.
 MOD_RES 1507 1507 Phosphoserine.
 MOD_RES 1691 1691 Phosphoserine (By similarity).
 MOD_RES 1754 1754 Phosphoserine.
 MOD_RES 1843 1843 Phosphoserine.
 CROSSLNK 1510 1510 Glycyl lysine isopeptide (Lys-Gly)  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Isopeptide bond; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2229 AA 
Protein Sequence
MSDRLGQITK GKDGKSKYST LSLFDKYKGK SVDAIRSSVI PRHGLQSLGK VAAARRMPPP 60
ANLPSLKSEN KGNDPNIVIV PKDGTGWANK QDQQDPKSSS ATASQPPESL PQPGLQKSVS 120
NLQKPTQSIS QENTNSVPGG PKSWAQLNGK PVGHEGGLRG SSRLLSFSPE EFPTLKAAGG 180
QDKAGKEKGV LDLSYGPGPS LRPQNVTSWR EGGGRHIISA TSLSTSPTEL GSRNSSTGDG 240
APSSACTSDS KDPSLRPAQP VRKGASQFMG NVYHPPTYHD MLPAFMCSPK SSENQGTVER 300
GSFPLPQLRL EPRVPFRQFQ MNDQDGKENR LGLSRPLRPL RQLVERAPRP TIINAENLKG 360
LDDLDADADD GWAGLHEEVD YSEKLKFSDD EEEEEVVKDG RPKWNSWDPR RQRQLSMSSA 420
DSADAKRTRE EGKDWAEAVG ASRVVRKAPD PQPPPRKLHG WAPGPDYQKS SMGSMFRQQS 480
IEDKEDKPPP RQKFIQSEMS EAVERARKRR EEEERRAREE RLAACAAKLK QLDQKCKQAR 540
KAGEARKQAE KEVPWSPSAE KASPQENGPA VHKGSPEFPA QETPTTFPEE APTVSPAVAQ 600
SNSSEEEARE AGSPAQEFKY QKSLPPRFQR QQQQQQQEQL YKMQHWQPVY PPPSHPQRTF 660
YPHHPQMLGF DPRWMMMPSY MDPRITPTRT PVDFYPSALH PSGLMKPMMP QESLNGTGCR 720
SEDQNCVPPL QERKVTPIDS PPVWSPEGYM ALQSKGYPLP HPKSSDTLAM DMRVRNESSF 780
SASLGRAGGV SAQRDLFEER GEEYLSAFDK KAQADFDSCI SSQRIGQELL FPPQENVQDA 840
GAPGGHTQNL RCSPLEPDFV PDEKKPECGS WDVSHQPETA DTAHGVERET PREGTAFNIS 900
SWDKNGSPNK QPSSEPEWTP EPRSSSSQHP EQTGRTRRSG PIKKPVLKAL KVEDKEKELE 960
KIKQELGEES TRLAKEKEQS PTAEKDEDEE NDASLANSST TTLEDKGPGH ATFGREATKF 1020
EEEEKPDKAW EARPPRESSD VPPMKRNNWI FIDEEQAFGV RGQARGRGRG FREFTFRGRP 1080
AGGNGSGLCG GGVLGARSIY CSSQRSGRGR GLREFARPED CPRAKPRRRV ASETHSEGSE 1140
YEELPKRRRQ RGSENGNEGS LLEREESTLK KGDCRDSWRS NKGCSEDHSG LDAKSRGPRA 1200
FGRALPPRLS NCGYGRRTFV SKESPHWQSK SPGSSWQEYG PSDTCGSRRP TDRDYVPDSY 1260
RHPDAFGGRG FEDSRAEDKR SFFQDEHVAD SENAENRPFR RRRPPRQDKP PRFRRLRQER 1320
ESLGLWGPEE EPHLLAGQWP GRPKLCSGDK SGTVGRRSPE LSYQNSSDHA NEEWETASES 1380
SDFSERRERR EGPGSEPDSQ VDGGLSGASL GEKKELAKRS FSSQRPVVDR QSRKLEPGGF 1440
GEKPVRPGGG DTSPRYESQQ NGTPLKVKRS PDEALPGGLS GCSSGSGHSP YALERAAHAS 1500
ADLPEASSKK AEKEAKLAAP RAGEQGEAMK QFDLNYGSAI IENCGSSPGE ESEVGSMVGE 1560
GFIEVLTKKQ RRLLEEERRK KEQAVQVPVK GRGLSSRIPP RFAKKQNNLC LEQGDVTVPG 1620
SSLGTEIWES SSQALPVQAP ANDSWRKAVT AFSSTETGSA EQGFKSSQGD SGVDLSAESR 1680
ESSATSSQRS SPYGTLKPEE MSGPGLAEPK ADSHKEQAPK PSEQKDSEQG SGQSKEHRPG 1740
PIGNERSLKN RKGSEGAERL QGAVVPPVNG VEIHVDSVLP VPPIEFGVSP KDSDFSLPPG 1800
SASGPTGSPV VKLQDALASN AGLTQSIPIL RRDHHIQRAI GLSPMSFPTA DLTLKMESAR 1860
KAWENSPSLP EQSSPGGAGS GIQPPSSVGA SSGVNYSSFG GVSMPPMPVA SVAPSASMPG 1920
SHLPPLYLDG HVFASQPRLV PQTIPQQQSY QQAAAAQQIP ISLHTSLQAQ AQLGLRGGLP 1980
VSQSQEIFSS LQPFRSQVYM HPSLSPPSTM ILSGGTALKP PYSAFPGMQP LEMVKPQSGS 2040
PYQPMSGNQA LVYEGQLSQA AGLGASQMLD SQLPQLTMPL PRYGSGQQPL ILPQSIQLPP 2100
GQSLSVGAPR RIPPPGSQPP VLNTSREPSQ MEMKGFHFAD SKQNVPSGGP VPSPQTYRPS 2160
SASPSGKPSG SAVNMGSVQG HYVQQAKQRV DEKPSLGAVK LQEAPSAASQ MKRTGAIKPR 2220
AVKVEESKA 2229 
Gene Ontology
  
Interpro
 IPR009738; BAT2_N. 
Pfam
 PF07001; BAT2_N 
SMART
  
PROSITE
  
PRINTS