CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035238
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Iqsec2 
Protein Synonyms/Alias
  
Gene Name
 Iqsec2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
708MKLDDFIKNLRGVDNubiquitination[1]
931YGAGDGLKRGALSSSubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 949 AA 
Protein Sequence
MEPPWKSSRS TASHTLHQYC CPTQVLDSMK LTPSGRLAES SVEGDAPGSD LSTAVDSPGS 60
QPPYRLSQLP PTSSHMGGPP AGVGLPWSQR ARLQPASVAL RKQEEEEIKR SKALSDSYEL 120
STDLQDKKVE MLERKYGGSF LSRRAARTIQ TAFRQYRMNK NFERLRSSAS ESRMSRRIIL 180
SNMRMQFSFE EYEKAQNPAY FEGKPASLDE GAMAGARSHR LERGLPYGGS CGGGIDGGGS 240
SVTTSGEFSN DITELEDSFS KQVKSLAESI DEALNCHPSG PMSEEPGSAQ LEKRESKEQQ 300
EDSSATSFSD LPLYLDDPVP PPSPERLPST EPPPQGRPEF WAPAPLPPVP PPMPPGTRED 360
GSREEGTRRG PGCLECRDFR LRAAHLPLLT IEPPSDSSVD LSDRSDRGSV HRQLVYEADG 420
CSPHGTLKHK GPPGRAPIPH RHYPAPEGPA PAPPGPLPPA PNSGTGPSGV AGGRRLGKCE 480
AAGENSDGGD NESLESSSNS NETINCSSGS SSRDSLREPP ATGLCKQTYQ RETRHSWDSP 540
AFNNDVVQRR HYRIGLNLFN KKPEKGIQYL IERGFLSDTP VGVAHFILER KGLSRQMIGE 600
FLGNRQKQFN RDVLDCVVDE MDFSSMDLDD ALRKFQSHIR VQGEAQKVER LIEAFSQRYC 660
VCNPALVRQF RNPDTIFILA FAIILLNTDM YSPSVKAERK MKLDDFIKNL RGVDNGEDIP 720
RDLLVGIYQR IQGRELRTND DHVSQVQAVE RMIVGKKPVL SLPHRRLVCC CQLYEVPDPN 780
RPQRLGLHQR EVFLFNDLLV VTKIFQKKKI LVTYSFRQSF PLVEMHMQLF QNSYYQFGIK 840
LLSAVPGGER KVLIIFNAPS LQDRLRFTSD LRESIAEVQE MEKYRVESEL EKQKGMMRPN 900
ASQPGGAKDS VNGTLARSSL EDTYGAGDGL KRGALSSSLR DLSDAGVCY 949 
Gene Ontology
 GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. 
Interpro
 IPR000048; IQ_motif_EF-hand-BS.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR000904; Sec7.
 IPR023394; SEC7_alpha_orthog. 
Pfam
 PF01369; Sec7 
SMART
 SM00233; PH
 SM00222; Sec7 
PROSITE
 PS50096; IQ
 PS50190; SEC7 
PRINTS