CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027631
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Akr1c20 protein 
Protein Synonyms/Alias
 Aldo-keto reductase; MCG9092, isoform CRA_c; Protein Akr1c20 
Gene Name
 Akr1c20 
Gene Synonyms/Alias
 mCG_9092 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
4****MNSKQQTVLLNubiquitination[1]
161CKDAGLAKSIGVCNFubiquitination[1]
179QLEKILSKPGLKYKPubiquitination[1]
185SKPGLKYKPVCNQVEubiquitination[1]
201HPYLNQRKLLDFCRSubiquitination[1]
230RDKEWVDKSFPVLLDubiquitination[1]
246PVLGSMAKKYNRTPAubiquitination[1]
301KVLDGLNKNIRYIGSubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 ACT_SITE 55 55 Proton donor (By similarity).  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 323 AA 
Protein Sequence
MNSKQQTVLL NDGHFIPILG FGTSAPQEVP RSKATEATKI AIDAGFRHID CAAVYQNEKE 60
VGLAIRSKIV DGTVKREDIF CTSKVWQTFH RPELVQVCLE QSLKQLQLDY VDLYLIHFPI 120
AMKPGENYFP KDENGKFIYD AVDICDTWEA MEKCKDAGLA KSIGVCNFNR RQLEKILSKP 180
GLKYKPVCNQ VECHPYLNQR KLLDFCRSKD IVLVAHSALG SNRDKEWVDK SFPVLLDDPV 240
LGSMAKKYNR TPALIALRYQ VQRGVVVLAK SFIEKRIKEN MQVFEFQLTS VDMKVLDGLN 300
KNIRYIGSSI SEDHPDFPFL DEY 323 
Gene Ontology
 GO:0004033; F:aldo-keto reductase (NADP) activity; ISA:MGI.
 GO:0006694; P:steroid biosynthetic process; ISA:MGI. 
Interpro
 IPR001395; Aldo/ket_red.
 IPR018170; Aldo/ket_reductase_CS.
 IPR020471; Aldo/keto_reductase_subgr.
 IPR023210; NADP_OxRdtase_dom. 
Pfam
 PF00248; Aldo_ket_red 
SMART
  
PROSITE
 PS00798; ALDOKETO_REDUCTASE_1
 PS00062; ALDOKETO_REDUCTASE_2 
PRINTS
 PR00069; ALDKETRDTASE.