CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008867
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glucose-6-phosphate 1-dehydrogenase 
Protein Synonyms/Alias
 G6PD; Vegetative protein 11; VEG11 
Gene Name
 zwf 
Gene Synonyms/Alias
 yqjJ; BSU23850 
Created Date
 July 27, 2013 
Organism
 Bacillus subtilis (strain 168) 
NCBI Taxa ID
 224308 
Lysine Modification
Position
Peptide
Type
References
149WSRLVIEKPFGHDLPacetylation[1]
Reference
 [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis.
 Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG.
 Proteomics. 2013 May;13(10-11):1726-36. [PMID: 23468065] 
Functional Description
  
Sequence Annotation
 ACT_SITE 241 241 Proton acceptor (By similarity).
 BINDING 17 17 NADP (By similarity).
 BINDING 49 49 NADP (By similarity).
 BINDING 179 179 Substrate (By similarity).
 BINDING 183 183 Substrate (By similarity).
 BINDING 346 346 Substrate (By similarity).  
Keyword
 Carbohydrate metabolism; Complete proteome; Direct protein sequencing; Glucose metabolism; NADP; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 489 AA 
Protein Sequence
MKTNQQPKAV IVIFGATGDL AKRKLYPSIH RLYQNGQIGE EFAVVGVGRR PWSNEDLRQT 60
VKTSISSSAD KHIDDFTSHF YYHPFDVTNP GSYQELNVLL NQLEDTYQIP NNRMFYLAMA 120
PEFFGTIAKT LKSEGVTATT GWSRLVIEKP FGHDLPSAQA LNKEIREAFT EDQIYRIDHY 180
LGKQMVQNIE VIRFANAIFE PLWTNRYISN IQITSSESLG VEDRARYYEK SGALRDMVQN 240
HIMQMVALLA MEPPIKLNTE EIRSEKVKVL RALRPIAKDE VDEYFVRGQY HAGEIDGVPV 300
PAYTDEDNVA PDSNTETFVA GKLLIDNFRW AGVPFYIRTG KRMKEKSTKI VVQFKDIPMN 360
LYYGNENNMN PNLLVIHIQP DEGITLYLNA KKLGGAAHAQ PIKLDYCSNC NDELNTPEAY 420
EKLIHDCLLG DATNFAHWDE VALSWSFVDS ISETWAANKT LSPNYESGSM GPKESDDLLV 480
KDGLHWWNI 489 
Gene Ontology
 GO:0004345; F:glucose-6-phosphate dehydrogenase activity; IEA:EC.
 GO:0050661; F:NADP binding; IEA:InterPro.
 GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway. 
Interpro
 IPR001282; G6P_DH.
 IPR019796; G6P_DH_AS.
 IPR022675; G6P_DH_C.
 IPR022674; G6P_DH_NAD-bd.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF02781; G6PD_C
 PF00479; G6PD_N 
SMART
  
PROSITE
 PS00069; G6P_DEHYDROGENASE 
PRINTS
 PR00079; G6PDHDRGNASE.