CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031599
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Autoantigen La 
Protein Synonyms/Alias
  
Gene Name
 SSB 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
116KNRSVYIKGFPTDATubiquitination[1]
176ETPGQKYKETDLLILubiquitination[1]
328DQQESLNKWKSKGRRubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 408 AA 
Protein Sequence
MAENGDNEKM AALEAKICHQ IEYYFGDFNL PRDKFLKEQI KLDEGWVPLE IMIKFNRLNR 60
LTTDFNVIVE ALSKSKAELM EISEDKTKIR RSPSKPLPEV TDEYKNDVKN RSVYIKGFPT 120
DATLDDIKEW LEDKGQVLNI QMRRTLHKAF KGSIFVVFDS IESAKKFVET PGQKYKETDL 180
LILFKDDYFA KKNEERKQNK VETKLRAKQE QEAKQKLEED AEMKSLEEKI GCLLKFSGDL 240
DDQTCREDLH ILFSNHGEIK WIDFVRGAKE GIILFKEKAK EALGKAKDAN NGNLQLRNKE 300
VTWEVLEGEV EKEALKKIIE DQQESLNKWK SKGRRFKGKG KGNKAAQPGS GKGKVQFQGK 360
KTKFASDDEH DEHDENGATG PVKRAREETD KEEPASKQQK TENGAGDQ 408 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0030529; C:ribonucleoprotein complex; IEA:InterPro.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0006396; P:RNA processing; IEA:InterPro. 
Interpro
 IPR002344; Lupus_La.
 IPR006630; Lupus_La_RNA-bd.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR014886; RRM_3.
 IPR000504; RRM_dom.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF05383; La
 PF00076; RRM_1
 PF08777; RRM_3 
SMART
 SM00715; LA
 SM00360; RRM 
PROSITE
 PS50961; HTH_LA
 PS50102; RRM 
PRINTS
 PR00302; LUPUSLA.