CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026556
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Golgi-specific brefeldin A-resistance factor 1 
Protein Synonyms/Alias
 Prostaglandin E synthase 2 
Gene Name
 Gbf1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
605NTLNQQEKKETARPGubiquitination[1]
697PRELIEIKNKKKLLIacetylation[2]
953LEETIIQKAISGFRKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1861 AA 
Protein Sequence
MVDKNIYIIQ GEINIVVGAI KRNARWSTHI PLDEERDPLL HSFSNLKEVL NSVTELSEIE 60
PNVFLRPFLE VIRSEDTTGP ITGLALTSVN KFLSYALIDP THEGTAEGME NMADAVTHAR 120
FVGTDPASDE VVLMKILQVL RTLLLTPVGT HLTNESVCEI MQSCFRICFE MRLSELLRKS 180
AEHTLVDMVQ LLFTRLPQFK EEPKSYVGTN MKKLKMRAGG MSDSSKWKKQ KRSPRPPRHT 240
TKVTPGSELP TPNGATLPSN LTGGVPFIDA PTSISSASSE AASTVVSPCT DSGLELSSQT 300
TSKEDLTDLE QAGSPREITT SEPGSSEMGA SDQLDPQEGA HVEKAQSASV ESIPEVLEEC 360
TSPADHSDSA SVHDMDYVNP RGVRFTQSSQ KEGTALVPYG LPCIRELFRF LISLTNPHDR 420
HNSEVMIHMG LHLLTVALES APVAQCQTLL GLIKDEMCRH LFQLLSVERL NLYAASLRVC 480
FLLFESMREH LKFQLEMYIK KLMEIITVEN PKMPYEMKEM ALEAVVQLWR IPSFVTELYI 540
NYDCDYYCSN LFEDLTKLLS KNAFPVSGQL YTTHLLSLDA LLTVIDSTES HCQAKVLNTL 600
NQQEKKETAR PGFEAVDGNP ETNKSERATS DGKSTGVALD ARGLHFPSGG WLSTEHGKPG 660
CRDLEEAGDS GADKKFTRKP PRFSCLLPDP RELIEIKNKK KLLITGTEQF NQKPKKGIQF 720
LQEKGLLTIP MDNTEVAQWL RENPRLDKKM IGEFVSDRKN MDLLESFVST FSFQGLRLDE 780
ALRLYLEAFR LPGEAPVIHR LLEVFTEHWR SCNGSPFANS DACFALAYAV IMLNTDQHNH 840
NVRKQNAPMT LEEFRKNLKG VNGGKDFEQD ILEDMYHAIK NEEIVMPEEQ TGLVRENYVW 900
SVLLHRGASP EGVFLRVPPG SYDLDLFTMT WGPTIAALSY VFDKSLEETI IQKAISGFRK 960
CAMISAHYGL SDVFDNLIIS LCKFTALSSE SIENLPSVFG SNPKAHIAAK TVFHLAHRHG 1020
DILREGWKNI MEAMLQLFRA QLLPKAMVEV EDFVDPNGKI SLQREETPSN RGESTVLSFV 1080
SWLTLSGPEQ SSVRGPSTEN QEAKRVALDC IKQCDPEKMI TESKFLQLES LQELMKALVS 1140
VTPDEETYDE EDAAFCLEML LRIVLENRDR VGCVWQTVRD HLYHLCVQAQ DFCFLVERAV 1200
VGLLRLAIRL LRREEISGQV LLSLRILLLM KPSVLSRVSH QVAYGLHELL KTNAANIHSG 1260
DDWATLFTLL ECIGSGVKPP DALQATARAD APDAGAQSDS ELPSYHQNDV SLDRGYTSDS 1320
EVYTDHGRPG KIHRSATDAD MVNSGWLVVG KDDIDNSKPG AGLSRPGPSP LVNQYSLTVG 1380
LDLGPHDTKS LLKCVESLSF IVRDAAHITP DNFELCVKTL RIFVEASLNG GCKSQDKRSK 1440
SHKYDSKGNR FKKKPKEGSM LRRPRGSNQH ATRGGHSDEE EDEGVPASYH TVSLQVSQDL 1500
LDLMHTLHTR AASIYSSWAE EQRHLEGGGQ KIEADSRTLW AHCWCPLLQG IACLCCDARR 1560
QVRMQALTYL QRALLVHDLQ KLDALEWESC FNKVLFPLLT KLLENISPAD VGGMEETRMR 1620
ASTLLSKVFL QHLSPLLSLS TFAALWLTIL DFMDKYMHAG SSDLLSEAIP ESLKNMLLVM 1680
DTAEIFHSAD ARGGGPSALW EITWERIDCF LPHLRDELFK QTVIQDPMPA EPHSQKPLAS 1740
THLTSAAGDP RMPGHPPLPE IPSEMGVCDS EKPESTRAPS SSSPGSPMAS SPSKLSPAQE 1800
GPPPLTQPPL ILQPLTSPLQ VGVPPMTLPI ILNPALIEAT SPVPLLATPR PTDPIPTSEV 1860
N 1861 
Gene Ontology
 GO:0005801; C:cis-Golgi network; IEA:Compara.
 GO:0005788; C:endoplasmic reticulum lumen; IEA:Compara.
 GO:0005795; C:Golgi stack; IEA:Compara.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005777; C:peroxisome; IEA:Compara.
 GO:0005802; C:trans-Golgi network; IBA:RefGenome.
 GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
 GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; IBA:RefGenome. 
Interpro
 IPR000904; Sec7.
 IPR023394; SEC7_alpha_orthog. 
Pfam
 PF01369; Sec7 
SMART
 SM00222; Sec7 
PROSITE
 PS50190; SEC7 
PRINTS