CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030932
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Elongator complex protein 3 
Protein Synonyms/Alias
 cDNA FLJ58009, highly similar to Homo sapiens elongation protein 3 homolog (ELP3), mRNA; cDNA, FLJ78952, highly similar to Homo sapiens elongation protein 3 homolog (ELP3), mRNA 
Gene Name
 ELP3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
5***MPKLKAKPIRTAubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 475 AA 
Protein Sequence
MPKLKAKPIR TASGIAVVAV MCKPHRCPHI SFTGNICVYC PGGPDSDFEY STQSYTGYEP 60
TSMRAIRARY DPFLQTRHRI EQLKQLGHSV DKVEFIVMGG TFMALPEEYR DYFIRNLHDA 120
LSGHTSNNIY EAVKYSERSL TKCIGITIET RPDYCMKRHL SDMLTYGCTR LEIGVQSVYE 180
DVARDTNRGH TVKAVCESFH LAKDSGFKVV AHMMPDLPNV GLERDIEQFT EFFENPAFRP 240
DGLKLYPTLV IRGTGLYELW KSGRYKSYSP SDLVELVARI LALVPPWTRV YRVQRDIPMP 300
LVSSGVEHGN LRELALARMK DLGIQCRDVR TREVGIQEIH HKVRPYQVEL VRRDYVANGG 360
WETFLSYEDP DQDILIGLLR LRKCSEETFR FELGGGVSIV RELHVYGSVV PVSSRDPTKF 420
QHQGFGMLLM EEAERIAREE HGSGKIAVIS GVGTRNYYRK IGYRLQGPYM VKMLK 475 
Gene Ontology
 GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
 GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
 GO:0008152; P:metabolic process; IEA:GOC.
 GO:0030335; P:positive regulation of cell migration; IEA:Compara. 
Interpro
 IPR016181; Acyl_CoA_acyltransferase.
 IPR006638; Elp3/MiaB/NifB.
 IPR000182; GNAT_dom.
 IPR005910; Hist_AcTrfase_ELP3.
 IPR007197; rSAM.
 IPR023404; rSAM_horseshoe. 
Pfam
 PF00583; Acetyltransf_1
 PF04055; Radical_SAM 
SMART
 SM00729; Elp3 
PROSITE
 PS51186; GNAT 
PRINTS