CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013884
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ketol-acid reductoisomerase 
Protein Synonyms/Alias
 Acetohydroxy-acid isomeroreductase; Alpha-keto-beta-hydroxylacyl reductoisomerase 
Gene Name
 ilvC 
Gene Synonyms/Alias
 TTHA1211 
Created Date
 July 27, 2013 
Organism
 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) 
NCBI Taxa ID
 300852 
Lysine Modification
Position
Peptide
Type
References
55KGSRSWEKAEAAGLRacetylation[1]
Reference
 [1] Acetylome with structural mapping reveals the significance of lysine acetylation in Thermus thermophilus.
 Okanishi H, Kim K, Masui R, Kuramitsu S.
 J Proteome Res. 2013 Aug 1;. [PMID: 23901841] 
Functional Description
  
Sequence Annotation
 ACT_SITE 107 107 Potential.  
Keyword
 Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 337 AA 
Protein Sequence
MKIYYEHDAD LGFILGKKVA VLGFGSQGHA HALNLKDSGV DVRVGLRKGS RSWEKAEAAG 60
LRVLPVAEAV READVVMVLL PDEKQAQVYR EEVEPNLKEG GALAFAHGFN VHFGQIKPRK 120
DLDVWMVAPK GPGHLVRSEY QKGSGVPALV AVHQDASGSA FPTALAYAKA IGAARAGVIA 180
TTFKDETETD LFGEQAVLCG GLTRLIRAGF ETLVEAGYPP EMAYFETVHE VKLIVDLIYE 240
AGLKGMRYSI SNTAEYGDYT RGDLAVPLEE TKRRMREILR QIQSGEFARE WMLENQVGSP 300
VLEANRKRWA AHPIEEVGSR LRAMMPFLKA RVMEEVG 337 
Gene Ontology
 GO:0050662; F:coenzyme binding; IEA:InterPro.
 GO:0004455; F:ketol-acid reductoisomerase activity; IEA:HAMAP.
 GO:0009097; P:isoleucine biosynthetic process; IEA:HAMAP.
 GO:0009099; P:valine biosynthetic process; IEA:HAMAP. 
Interpro
 IPR008927; 6-PGluconate_DH_C-like.
 IPR013023; AcH_isomrdctse.
 IPR000506; AcH_isomrdctse_C.
 IPR013328; DH_multihelical.
 IPR013116; IlvN. 
Pfam
 PF01450; IlvC
 PF07991; IlvN 
SMART
  
PROSITE
  
PRINTS