| Tag | Content |
|---|
| CPLM ID | CPLM-003563 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | C4-dicarboxylic acid transporter DauA |
Protein Synonyms/Alias | Dicarboxylic acid uptake system A |
Gene Name | dauA |
Gene Synonyms/Alias | ychM; b1206; JW5189 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 493 | GKRIVILKWDAVPVL | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Responsible for the aerobic transport of succinate from the periplasm to the cytoplasm at acidic pH. Can transport other C4-dicarboxylic acids such as aspartate and fumarate. May also play a role in the regulation of C4-dicarboxylic acid metabolism at pH 7, via regulation of expression and/or activity of DctA. May act as a co-sensor of DcuS. |
Sequence Annotation | DOMAIN 449 559 STAS. |
Keyword | Cell inner membrane; Cell membrane; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 559 AA |
Protein Sequence | MNKIFSSHVM PFRALIDACW KEKYTAARFT RDLIAGITVG IIAIPLAMAL AIGSGVAPQY 60
GLYTAAVAGI VIALTGGSRF SVSGPTAAFV VILYPVSQQF GLAGLLVATL LSGIFLILMG 120
LARFGRLIEY IPVSVTLGFT SGIGITIGTM QIKDFLGLQM AHVPEHYLQK VGALFMALPT 180
INVGDAAIGI VTLGILVFWP RLGIRLPGHL PALLAGCAVM GIVNLLGGHV ATIGSQFHYV 240
LADGSQGNGI PQLLPQLVLP WDLPNSEFTL TWDSIRTLLP AAFSMAMLGA IESLLCAVVL 300
DGMTGTKHKA NSELVGQGLG NIIAPFFGGI TATAAIARSA ANVRAGATSP ISAVIHSILV 360
ILALLVLAPL LSWLPLSAMA ALLLMVAWNM SEAHKVVDLL RHAPKDDIIV MLLCMSLTVL 420
FDMVIAISVG IVLASLLFMR RIARMTRLAP VVVDVPDDVL VLRVIGPLFF AAAEGLFTDL 480
ESRLEGKRIV ILKWDAVPVL DAGGLDAFQR FVKRLPEGCE LRVCNVEFQP LRTMARAGIQ 540
PIPGRLAFFP NRRAAMADL 559 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0015106; F:bicarbonate transmembrane transporter activity; IMP:EcoCyc. GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro. GO:0006633; P:fatty acid biosynthetic process; IPI:EcoCyc. GO:0008272; P:sulfate transport; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |