UniProt Accession

 B4DUR0_HUMAN; B4DUR0 

Genbank Protein ID

 AL109921; BX248409; AK300755 

Genbank Nucleotide ID

 BAG62422.1 

Protein Name

 Kelch-like protein 20 

Protein Synonyms/Alias

 cDNA FLJ57439, highly similar to Kelch-like protein 20 

Gene Name

 KLHL20 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
76	RLPLLSPKFLVGTVG	ubiquitination	[1, 2, 3]
199	SVERYDPKTNQWSSD	ubiquitination	[3]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Kelch repeat; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 420 AA 

Protein Sequence

Gene Ontology

 GO:0005794; C:Golgi apparatus; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA. 

Interpro

 IPR011705; BACK.
 IPR015916; Gal_Oxidase_b-propeller.
 IPR006652; Kelch_1. 

Pfam

 PF07707; BACK
 PF01344; Kelch_1 

SMART

 SM00875; BACK
 SM00612; Kelch 

PROSITE

  

PRINTS